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Etalocib

CAS No. 161172-51-6

Etalocib ( LY293111; VML295 )

Catalog No. M23713 CAS No. 161172-51-6

Etalocib is a novel diaryl ether carboxylic acid derivative, is a selective and potent inhibitor of the lipoxygenase pathway either via antagonism of the leukotriene B4 (LTB4) receptor or directly through 5'-lipoxygenase.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Etalocib
  • Note
    Research use only, not for human use.
  • Brief Description
    Etalocib is a novel diaryl ether carboxylic acid derivative, is a selective and potent inhibitor of the lipoxygenase pathway either via antagonism of the leukotriene B4 (LTB4) receptor or directly through 5'-lipoxygenase.
  • Description
    Etalocib is a novel diaryl ether carboxylic acid derivative, is a selective and potent inhibitor of the lipoxygenase pathway either via antagonism of the leukotriene B4 (LTB4) receptor or directly through 5'-lipoxygenase. It has antineoplastic activities.
  • Synonyms
    LY293111; VML295
  • Pathway
    Apoptosis
  • Target
    Apoptosis
  • Recptor
    Apoptosis;LTB4
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    161172-51-6
  • Formula Weight
    544.6
  • Molecular Formula
    C33H33FO6
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:100 mg/mL (183.62 mM; Need ultrasonic)
  • SMILES
    O=C(O)C1=CC=CC=C1OC2=CC=CC(OCCCOC3=C(CC)C=C(C4=CC=C(F)C=C4)C(O)=C3)=C2CCC
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.P Marder, et al. Blockade of Human Neutrophil Activation by 2-[2-propyl-3-[3-[2-ethyl-4-(4-fluorophenyl)-5- Hydroxyphenoxy]propoxy]phenoxy]benzoic Acid (LY293111), a Novel Leukotriene B4 Receptor Antagonist. Biochem Pharmacol. 1995 May 26;49(11):1683-90.
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