Estriol ( E3; 16α-hydroxy-17β-estradiol; 1,3,5(10)-Estratriene-3,16α,17β-triol )

Catalog No. M14701 CAS No. 50-27-1

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Datasheet

HNMR

HPLC

MSDS

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Product Name

Estriol
Note

Research use only, not for human use.
Brief Description

Estriol is an antagonist of the G-protein coupled estrogen receptor in estrogen receptor-negative breast Y cells.
Description

Estriol is an antagonist of the G-protein coupled estrogen receptor in estrogen receptor-negative breast Y cells.
Synonyms

E3; 16α-hydroxy-17β-estradiol; 1,3,5(10)-Estratriene-3,16α,17β-triol
Pathway

Endocrinology/Hormones
Target

Estrogen Receptor/ERR
Recptor

ER; MRP1
Research Area

Cancer
Indication

——

CAS Number

50-27-1
Formula Weight

288.39
Molecular Formula

C18H24O3
Purity

>98%(HPLC)
Solubility

Ethanol: 10 mg/mL (34.67 mM); DMSO: 57 mg/mL (197.64 mM)
SMILES

OC1=CC=C2[C@@]3([H])CC[C@]4(C)[C@@H](O)[C@H](O)C[C@@]4([H])[C@]3([H])CCC2=C1
Chemical Name

(8R,9S,13S,14S,16R,17R)-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,16,17-triol

1.Lappano R, et al. Mol Cell Endocrinol. 2010, 320(1-2), 162-170.

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