Escin( —— )

Catalog No. M15597 CAS No. 6805-41-0

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Datasheet

HNMR

HPLC

MSDS

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Product Name

Escin
Note

Research use only, not for human use.
Brief Description

Pentacyclic triterpene saponins, biosynthesized from protoaescigenin and barringtogenol, occurring in the seeds of AESCULUS. It inhibits edema formation and decreases vascular fragility.
Description

Pentacyclic triterpene saponins, biosynthesized from protoaescigenin and barringtogenol, occurring in the seeds of AESCULUS. It inhibits edema formation and decreases vascular fragility.
In Vitro

Western Blot Analysis Cell Line:OGD/R and rt-PA stimulated bEnd.3 cells Concentration:0.1, 0.5 and 1 μg/mL Incubation Time:24 h Result:Upregulated the expression of ZO-1 and Occludin.
In Vivo

Animal Model:Con A-induced immune-mediated hepatitis mice Dosage:10 mg/kg Administration:p.o., 4 days Result:Decreased the peak activities of ALT (p?
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

Others
Research Area

Other Indications
Indication

——

CAS Number

6805-41-0
Formula Weight

1131.28
Molecular Formula

C55H86O24
Purity

>98% (HPLC)
Solubility

Soluble in Water
SMILES

CC=C(C)C(=O)OC1C([C@@]2(C(C[C@@]3(C(=CCC4[C@]3(CCC5[C@@]4(CCC([C@]5(C)CO)OC6C(C(C(C(O6)C(=O)O)OC7C(C(C(C(O7)CO)O)O)O)O)OC8C(C(C(C(O8)CO)O)O)O)C)C)C2CC1(C)C)C)O)CO)OC(=O)C
Chemical Name

——

1.Yu Z, Su P. Pharmazie. 2013 Jun;68(6):428-30.

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