
Escin
CAS No. 6805-41-0
Escin( —— )
Catalog No. M15597 CAS No. 6805-41-0
Pentacyclic triterpene saponins, biosynthesized from protoaescigenin and barringtogenol, occurring in the seeds of AESCULUS. It inhibits edema formation and decreases vascular fragility.
Purity : >98% (HPLC)






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Biological Information
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Product NameEscin
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NoteResearch use only, not for human use.
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Brief DescriptionPentacyclic triterpene saponins, biosynthesized from protoaescigenin and barringtogenol, occurring in the seeds of AESCULUS. It inhibits edema formation and decreases vascular fragility.
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DescriptionPentacyclic triterpene saponins, biosynthesized from protoaescigenin and barringtogenol, occurring in the seeds of AESCULUS. It inhibits edema formation and decreases vascular fragility.
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In VitroWestern Blot Analysis Cell Line:OGD/R and rt-PA stimulated bEnd.3 cells Concentration:0.1, 0.5 and 1 μg/mL Incubation Time:24 h Result:Upregulated the expression of ZO-1 and Occludin.
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In VivoAnimal Model:Con A-induced immune-mediated hepatitis mice Dosage:10 mg/kg Administration:p.o., 4 days Result:Decreased the peak activities of ALT (p?
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research AreaOther Indications
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Indication——
Chemical Information
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CAS Number6805-41-0
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Formula Weight1131.28
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Molecular FormulaC55H86O24
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Purity>98% (HPLC)
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SolubilitySoluble in Water
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SMILESCC=C(C)C(=O)OC1C([C@@]2(C(C[C@@]3(C(=CCC4[C@]3(CCC5[C@@]4(CCC([C@]5(C)CO)OC6C(C(C(C(O6)C(=O)O)OC7C(C(C(C(O7)CO)O)O)O)O)OC8C(C(C(C(O8)CO)O)O)O)C)C)C2CC1(C)C)C)O)CO)OC(=O)C
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Yu Z, Su P. Pharmazie. 2013 Jun;68(6):428-30.
molnova catalog



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