
Erianin
CAS No. 95041-90-0
Erianin( —— )
Catalog No. M19283 CAS No. 95041-90-0
Erianin is a nature product extracted from Dendrobium chrysotoxum, has notable antitumour activity, can cause extensive tumour necrosis, growth delay.
Purity : >98% (HPLC)






Size | Price / USD | Stock | Quantity |
5MG | 37 | In Stock |
![]() ![]() |
10MG | 59 | In Stock |
![]() ![]() |
25MG | 87 | In Stock |
![]() ![]() |
50MG | 119 | In Stock |
![]() ![]() |
100MG | 176 | In Stock |
![]() ![]() |
200MG | Get Quote | In Stock |
![]() ![]() |
500MG | Get Quote | In Stock |
![]() ![]() |
1G | Get Quote | In Stock |
![]() ![]() |
Biological Information
-
Product NameErianin
-
NoteResearch use only, not for human use.
-
Brief DescriptionErianin is a nature product extracted from Dendrobium chrysotoxum, has notable antitumour activity, can cause extensive tumour necrosis, growth delay.
-
DescriptionErianin is a nature product extracted from Dendrobium chrysotoxum, has notable antitumour activity , can cause extensive tumour necrosis, growth delay. Erianin has antiangiogenic action by inhibiting endothelial metabolism in a JNK/SAPK-dependent manner and inducing endothelial cytoskeletal disorganisation. Erianin shows potent inhibitory activity on the proliferation of HL-60 cells, the inhibition might be relative to the apoptosis induced by Erianin and the altered expression of bcl-2 and bax genes in HL-60 cells.
-
In VitroErianin is often used as antipyretic and analgesic agent. Erianin belongs to bibenzyl derivatives in structure, with the activity of anti-virus, anti-bacterial, as well as anti-benign prostatic hyperplasia. Erianin has obvious damage on 2LL-IDO cells, Erianin basically has no cytotoxicity on human normal liver cell line L02, and cell viability is maintained at around 85%. Erianin inhibits the growth of HeLa cells and induces apoptosis in a dose? and time?dependent manner, inducing cell cycle arrest at the G2/M stage. Erianin treatment also increases the expression of Bax and caspase?3, but decreases levels of Bcl?2 and phosphorylated?ERK1/2.
-
In Vivo——
-
Synonyms——
-
PathwayOthers
-
TargetOther Targets
-
RecptorBcl-2
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number95041-90-0
-
Formula Weight318.37
-
Molecular FormulaC18H22O5
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 100 mg/mL (314.11 mM)
-
SMILESCOc1c(cc(cc1)CCc1cc(c(c(c1)OC)OC)OC)O
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Lam F,et al. ZJU-6, a novel derivative of Erianin, shows potent anti-tubulin polymerisation and anti-angiogenic activities. Invest New Drugs. 2012 Oct;30(5):1899-907.
molnova catalog



related products
-
Sarmazenil
Sarmazenil (Ro 15-3505) is a partial inverse agonist at the benzodiazepine receptor with pro-convulsant properties and is used in the study of chronic hepatic encephalopathy (HE).
-
Filorexant
Filorexant is an orally bioavailable effective and selective reversible antagonist of OX1 and OX2 receptor with (Ki <3 nM).
-
MSC 2032964A
MSC 2032964A is a potent selective ASK1 inhibitor (IC50 = 93 nM) that is oral bioavailable and brain permeable. It inhibited neuroinflammation in mouse EAE models and blocked LPS-induced phosphorylation of ASK1 and p38 in cultured mouse astrocytes.