ErSO
CAS No. 2407860-35-7
ErSO ( —— )
Catalog No. M28247 CAS No. 2407860-35-7
ErSO is a selective activator of anticipatory unfolded protein response (UPR) via ERα receptor. ErSO can be used in studies about anti-cancer.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 260 | Get Quote |
|
10MG | 417 | Get Quote |
|
25MG | 687 | Get Quote |
|
50MG | 963 | Get Quote |
|
100MG | 1287 | Get Quote |
|
500MG | 2601 | Get Quote |
|
1G | Get Quote | Get Quote |
|
Biological Information
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Product NameErSO
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NoteResearch use only, not for human use.
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Brief DescriptionErSO is a selective activator of anticipatory unfolded protein response (UPR) via ERα receptor. ErSO can be used in studies about anti-cancer.
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DescriptionErSO is a selective activator of anticipatory unfolded protein response (UPR) via ERα receptor. ErSO can be used in studies about anti-cancer.(In Vitro):In MCF-7 cells, ErSO (1-1000 nM) inhibits cell viability with an IC50 of 20.3 nM. ErSO (1 μM) rapidly kills ERα-positive breast cancer cells in TYS and TDG cells and induces rapid killing of ERα-positive MCF-7 human breast cancer cells.(In Vivo):ErSO (10 and 40 mg/kg; p.o.) induces >100000-fold regression (to undetectable amounts) within 14 days and >10000-fold regression of TYS-luciferase-expressing breast tumors in all five mice. In Nu/J mice, ErSO (10 or 40 mg/kg; p.o.) eliminates tumors with >90% reduction in all cases.
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Synonyms——
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PathwayOthers
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TargetOther Targets
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Recptorγ secretase
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Research Area——
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Indication——
Chemical Information
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CAS Number2407860-35-7
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Formula Weight453.3
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Molecular FormulaC22H13F6NO3
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C1[C@@](C=2C(N1)=C(C(F)(F)F)C=CC2)(C3=CC=C(OC(F)(F)F)C=C3)C4=CC=C(O)C=C4
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Baumann, et al. Preparation of 4,5,6,7-tetrahydrobenzothiazolyl- or 5,6,7,8-tetrahydroquinazolinylphenylamine derivatives as modulators for amyloid beta. WO2009087127A1
molnova catalog
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