Enpp-1-IN-14
CAS No. 2687222-59-7
Enpp-1-IN-14 ( —— )
Catalog No. M28549 CAS No. 2687222-59-7
ENPP1-IN-2 is a potent inhibitor of Ectonucleotide Pyrophosphatase/Phosphodiesterase-1 (ENPP1) with an IC50 value of 32.38 nM for recombinant human ENPP-1. ENPP1-IN-2 has anti-tumor activity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 110 | Get Quote |
|
10MG | 177 | Get Quote |
|
25MG | 410 | Get Quote |
|
50MG | 605 | Get Quote |
|
100MG | 860 | Get Quote |
|
200MG | Get Quote | Get Quote |
|
500MG | Get Quote | Get Quote |
|
1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameEnpp-1-IN-14
-
NoteResearch use only, not for human use.
-
Brief DescriptionENPP1-IN-2 is a potent inhibitor of Ectonucleotide Pyrophosphatase/Phosphodiesterase-1 (ENPP1) with an IC50 value of 32.38 nM for recombinant human ENPP-1. ENPP1-IN-2 has anti-tumor activity.
-
DescriptionENPP1-IN-2 is a potent inhibitor of Ectonucleotide Pyrophosphatase/Phosphodiesterase-1 (ENPP1) with an IC50 value of 32.38 nM for recombinant human ENPP-1. ENPP1-IN-2 has anti-tumor activity.(In Vivo):ENPP1-IN-2 (compound 015) (50 mg/kg; IP; BID, for 31 days) significantly inhibits tumor growth in Female C57BL/6 mice (4-6 weeks; implanted subcutaneously with 2×105 MC38 cells).
-
Synonyms——
-
PathwayAngiogenesis
-
TargetPDE
-
RecptorKSP
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2687222-59-7
-
Formula Weight403.9
-
Molecular FormulaC15H22ClN5O4S
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESCl.O=S(=O)(N)N1CCN(C=2N=CN=C3C=C(OC)C(OC)=CC32)CCC1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Woessner R, et al. ARRY-520, a novel KSP inhibitor with potent activity in hematological and taxane-resistant tumor models. Anticancer Res. 2009 Nov;29(11):4373-80.
molnova catalog
related products
-
HT-0712
HT-0712 (IPL-455903) is a novel potent, selective PDE4 inhibitor with IC50 of 0.15 uM for PDE4D3.
-
MBCQ
MBCQ is an inhibitor of cGMP-specific phosphodiesterase PDE5.MBCQ, a selective PDE5 inhibitor, significantly decreased the EC(50) values for GTN-induced relaxation in both tolerant and nontolerant tissues, but with the greatest relative shift occurring in tolerant veins.
-
Piclamilast
Piclamilast is a PDE4 inhibitor.