Enpp-1-IN-14

CAS No. 2687222-59-7

Enpp-1-IN-14 ( —— )

Catalog No. M28549 CAS No. 2687222-59-7

ENPP1-IN-2 is a potent inhibitor of Ectonucleotide Pyrophosphatase/Phosphodiesterase-1 (ENPP1) with an IC50 value of 32.38 nM for recombinant human ENPP-1. ENPP1-IN-2 has anti-tumor activity.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 110 Get Quote
10MG 177 Get Quote
25MG 410 Get Quote
50MG 605 Get Quote
100MG 860 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    Enpp-1-IN-14
  • Note
    Research use only, not for human use.
  • Brief Description
    ENPP1-IN-2 is a potent inhibitor of Ectonucleotide Pyrophosphatase/Phosphodiesterase-1 (ENPP1) with an IC50 value of 32.38 nM for recombinant human ENPP-1. ENPP1-IN-2 has anti-tumor activity.
  • Description
    ENPP1-IN-2 is a potent inhibitor of Ectonucleotide Pyrophosphatase/Phosphodiesterase-1 (ENPP1) with an IC50 value of 32.38 nM for recombinant human ENPP-1. ENPP1-IN-2 has anti-tumor activity.(In Vivo):ENPP1-IN-2 (compound 015) (50 mg/kg; IP; BID, for 31 days) significantly inhibits tumor growth in Female C57BL/6 mice (4-6 weeks; implanted subcutaneously with 2×105 MC38 cells).
  • Synonyms
    ——
  • Pathway
    Angiogenesis
  • Target
    PDE
  • Recptor
    KSP
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2687222-59-7
  • Formula Weight
    403.9
  • Molecular Formula
    C15H22ClN5O4S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    Cl.O=S(=O)(N)N1CCN(C=2N=CN=C3C=C(OC)C(OC)=CC32)CCC1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Woessner R, et al. ARRY-520, a novel KSP inhibitor with potent activity in hematological and taxane-resistant tumor models. Anticancer Res. 2009 Nov;29(11):4373-80.
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