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Encenicline

CAS No. 550999-75-2

Encenicline ( EVP-6124 )

Catalog No. M20623 CAS No. 550999-75-2

Encenicline is a selective α7 nicotinic acetylcholine receptor?(nAChRs) agonist in development for treating cognitive impairment in schizophrenia and Alzheimer's disease.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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5MG 214 Get Quote
10MG 347 Get Quote
25MG 581 Get Quote
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Biological Information

  • Product Name
    Encenicline
  • Note
    Research use only not for human use.
  • Brief Description
    Encenicline is a selective α7 nicotinic acetylcholine receptor?(nAChRs) agonist in development for treating cognitive impairment in schizophrenia and Alzheimer's disease.
  • Description
    Encenicline is a selective α7 nicotinic acetylcholine receptor?(nAChRs) agonist in development for treating cognitive impairment in schizophrenia and Alzheimer's disease.
  • Synonyms
    EVP-6124
  • Pathway
    Endocrinology/Hormones
  • Target
    AChR
  • Recptor
    nAChR
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    550999-75-2
  • Formula Weight
    320.84
  • Molecular Formula
    C16H17ClN2OS
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    Clc1cccc2cc(sc12)C(=O)N[C@H]1CN2CCC1CC2
  • Chemical Name
    N-[(3R)-1-Azabicyclo[2.2.2]octan-3-yl]-7-chloro-1-benzothiophene-2-carboxamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Prickaerts J van Goethem NP Chesworth Ret al.EVP-6124 a novel and selective α7 nicotinic acetylcholine receptor partial agonist improves memory performance by potentiating the acetylcholine response of α7 nicotinic acetylcholine receptors[J].Neuropharmacology. 2012 Feb;62(2):1099-110.
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