Emzadirib

CAS No. 2301085-04-9

Emzadirib( —— )

Catalog No. M33099 CAS No. 2301085-04-9

Emzadirib (RAD51-IN-2) is a potent inhibitor of RAD51, showing potential anticancer activity and useful for studying DNA damage repair.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Emzadirib
  • Note
    Research use only, not for human use.
  • Brief Description
    Emzadirib (RAD51-IN-2) is a potent inhibitor of RAD51, showing potential anticancer activity and useful for studying DNA damage repair.
  • Description
    Emzadirib (RAD51-IN-2) is a RAD51 inhibitor extracted from patent WO2019/051465A1.
  • In Vitro
    Emzadirib exhibts an EC50 of ≤1 μM in activation-induced cytidine deaminase (AID) positive cells.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    DNA/RNA Synthesis
  • Recptor
    DNA/RNA Synthesis
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2301085-04-9
  • Formula Weight
    580.76
  • Molecular Formula
    C27H40N4O6S2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (172.19 mM; Ultrasonic )
  • SMILES
    CC(C)OC(=O)N[C@H]1CC[C@@H](CC1)c1ncc(s1)-c1ccc(NC(=O)OC(C)C)cc1S(=O)(=O)NC(C)(C)C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Alfredo C. Castro, et al. Rad51 inhibitors. WO2019/051465A1.
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