Cart
sales@molnova.com
Eliprodil
CAS No. 119431-25-3
Eliprodil( SL-820715 )
Catalog No. M10679 CAS No. 119431-25-3
Eliprodil (SL-820715) is a non-competitive NR2B-NMDA receptor antagonist, less potent for NR2A- and NR2C-containing receptors (IC50>100 uM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 46 | In Stock |
|
| 10MG | 83 | In Stock |
|
| 25MG | 159 | In Stock |
|
| 50MG | 304 | In Stock |
|
| 100MG | 462 | In Stock |
|
| 500MG | 972 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameEliprodil
-
NoteResearch use only, not for human use.
-
Brief DescriptionEliprodil (SL-820715) is a non-competitive NR2B-NMDA receptor antagonist, less potent for NR2A- and NR2C-containing receptors (IC50>100 uM).
-
DescriptionEliprodil (SL-820715) is a non-competitive NR2B-NMDA receptor antagonist, less potent for NR2A- and NR2C-containing receptors (IC50>100 uM); inhibits [3H]norepinephrine release from cortical and hippocampal slices but enhances the basal efflux of endogenous and tritiated dopamine from striatal slices, also blocks the uptake of [3H]dopamine into striatal synaptosomes with IC50 of 1.5 uM; reduces the volume of infarction in models of focal cerebral ischemia.Stroke Phase 3 Discontinued.
-
In Vitro——
-
In Vivo——
-
SynonymsSL-820715
-
PathwayMembrane Transporter/Ion Channel
-
TargetiGluR
-
RecptorNR2B-NMDA
-
Research AreaNeurological Disease
-
IndicationStroke
Chemical Information
-
CAS Number119431-25-3
-
Formula Weight347.8541
-
Molecular FormulaC20H23ClFNO
-
Purity>98% (HPLC)
-
Solubility10 mM in DMSO
-
SMILESOC(C1=CC=C(Cl)C=C1)CN2CCC(CC3=CC=C(F)C=C3)CC2
-
Chemical Name1-Piperidineethanol, α-(4-chlorophenyl)-4-[(4-fluorophenyl)methyl]-
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Woodward JJ, et al. Eur J Pharmacol. 1992 Jan 21;210(3):265-70.
2. Carter CJ, et al. J Pharmacol Exp Ther. 1990 May;253(2):475-82.
3. Carter C, et al. Eur J Pharmacol. 1989 May 30;164(3):611-2.
4. Bath CP, et al. Eur J Pharmacol. 1996 Mar 28;299(1-3):103-12.
molnova catalog
related products
-
(S)-Willardiine
(S)-Willardiine (L-willardiine) is present in the seeds of Acacia and Mimosa. (S)-Willardiine is an AMPA/kainate receptor agonist (EC50 = 44.8 μM).
-
LY450108
LY450108 is a potentiator of the AMPA receptor that can be used in Parkinson's disease studies.
-
AMPA receptor antago...
AMPA receptor antagonist-2 is an AMPA receptor antagonist.
