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Elesclomol
CAS No. 488832-69-5
Elesclomol ( STA-4783;STA4783;STA 4783 )
Catalog No. M14641 CAS No. 488832-69-5
Elesclomol (STA-4783) is a small-molecule oxidative stress inducer.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 31 | In Stock |
|
| 10MG | 53 | In Stock |
|
| 25MG | 85 | In Stock |
|
| 50MG | 115 | In Stock |
|
| 100MG | 147 | In Stock |
|
| 200MG | 219 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameElesclomol
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NoteResearch use only, not for human use.
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Brief DescriptionElesclomol (STA-4783) is a small-molecule oxidative stress inducer.
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DescriptionElesclomol (STA-4783) is a small-molecule oxidative stress inducer, exerts selective cytotoxicity by increasing intracellular concentrations of reactive oxygen species (ROS) and induces cell death via mitochondrial apoptosisin cancer cells; selectively kills cisplatin-resistant tumor cells through increased ROS, markedly enhances the therapeutic index of paclitaxel against human tumor xenograft models. Ovarian Cancer Phase 2 Clinical
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SynonymsSTA-4783;STA4783;STA 4783
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PathwayApoptosis
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TargetApoptosis
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RecptorHSP70
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Research AreaCancer
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IndicationOvarian Cancer
Chemical Information
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CAS Number488832-69-5
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Formula Weight400.52
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Molecular FormulaC19H20N4O2S2
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Purity>98% (HPLC)
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SolubilityDMSO: ≥ 22 mg/mL
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SMILESO=C(NN(C)C(C1=CC=CC=C1)=S)CC(NN(C)C(C2=CC=CC=C2)=S)=O
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Chemical NamePropanedioic acid, 1,3-bis[2-methyl-2-(phenylthioxomethyl)hydrazide]
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Berkenblit A, et al. Clin Cancer Res. 2007 Jan 15;13(2 Pt 1):584-90.
2. Kirshner JR, et al. Mol Cancer Ther. 2008 Aug;7(8):2319-27.
3. Wangpaichitr M, et al. Cancers (Basel). 2009;1(1):23-38.
4. Kluza J, et al. Cancer Res. 2012 Oct 1;72(19):5035-47.
2. Kirshner JR, et al. Mol Cancer Ther. 2008 Aug;7(8):2319-27.
3. Wangpaichitr M, et al. Cancers (Basel). 2009;1(1):23-38.
4. Kluza J, et al. Cancer Res. 2012 Oct 1;72(19):5035-47.
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