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Echinatin
CAS No. 34221-41-5
Echinatin ( Echinatin; Retrochalcone )
Catalog No. M18446 CAS No. 34221-41-5
Echinatin disturb the mitochondrial energy transfer reactions and membrane permeability, at a low concentration cause deterioration of respiratory control and oxidative phosphorylation of isolated rat liver mitochondria.
Purity : 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 10MG | 108 | In Stock |
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| 100MG | Get Quote | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameEchinatin
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NoteResearch use only, not for human use.
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Brief DescriptionEchinatin disturb the mitochondrial energy transfer reactions and membrane permeability, at a low concentration cause deterioration of respiratory control and oxidative phosphorylation of isolated rat liver mitochondria.
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DescriptionEchinatin disturb the mitochondrial energy transfer reactions and membrane permeability, at a low concentration cause deterioration of respiratory control and oxidative phosphorylation of isolated rat liver mitochondria, inhibits DNP-ATPase activity while stimulating range latent ATPase activity. Echinatin has significant antioxidant activities, it shows strong scavenging activity toward the ABTS + radical, it also dose-dependently inhibits LPS induced reactive oxygen species (ROS) production in RAW 264.7 cells and inhibits the production of nitric oxide (NO), interleukin-6 (IL-6) and prostaglandin E2 (PGE2) in LPS-induced macrophage cells.
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SynonymsEchinatin; Retrochalcone
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PathwayOthers
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TargetOther Targets
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RecptorFree radical scavengers
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Research AreaOthers-Field
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Indication——
Chemical Information
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CAS Number34221-41-5
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Formula Weight270.28
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Molecular FormulaC16H14O4
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Purity98%
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Solubility——
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SMILESCOc2cc(O)ccc2/C=C/C(=O)c1ccc(O)cc1
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Chemical Name(E)-3-(4-hydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)prop-2-en-1-one
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Inoue B, et al. The effects of echinatin and its related compounds on the mitochondrial energy transfer reaction.[J]. Journal of Toxicological Sciences, 1982, 7(4):245.
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