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EX-229
CAS No. 1219739-36-2
EX-229( EX 229 | EX229 )
Catalog No. M10829 CAS No. 1219739-36-2
A small molecule AMPK activator that dose-dependently increases AMPK activity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 40 | Get Quote |
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| 5MG | 61 | Get Quote |
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| 10MG | 102 | Get Quote |
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| 25MG | 210 | Get Quote |
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| 50MG | 356 | Get Quote |
|
| 100MG | 536 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameEX-229
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NoteResearch use only, not for human use.
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Brief DescriptionA small molecule AMPK activator that dose-dependently increases AMPK activity.
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DescriptionA small molecule AMPK activator that dose-dependently increases AMPK activity of α1-, α2-, β1- and β2-containing complexes at 50 uM; induces AMPK activation and glucose uptak in a wortmannin-independent manner; increases fatty acid oxidation in L6 myotubes.
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In Vitro——
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In Vivo——
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SynonymsEX 229 | EX229
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PathwayMembrane Transporter/Ion Channel
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TargetAMPK
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RecptorAMPK
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Research Area——
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Indication——
Chemical Information
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CAS Number1219739-36-2
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Formula Weight431.876
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Molecular FormulaC24H18ClN3O3
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Purity>98% (HPLC)
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SolubilityDMSO : 5.4 mg/mL12.50 mM
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SMILESO=C(O)C1=CC(OC2=NC3=CC(C4=CC5=C(N(C)C=C5)C=C4)=C(Cl)C=C3N2)=CC=C1C
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Chemical Name5-{[6-chloro-5-(1-methylindol-5-yl)-1H-benzimidazol-2-yl]oxy}-2-methyl-benzoic acid
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Lai YC, et al. Biochem J. 2014 Jun 15;460(3):363-75.
2. Bultot L, et al. Am J Physiol Endocrinol Metab. 2016 Oct 1;311(4):E706-E719.
3. Patent WO2010036613, EX229.
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