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ESI-09
CAS No. 263707-16-0
ESI-09( ESI09 | ESI 09 | ESI-09 )
Catalog No. M13808 CAS No. 263707-16-0
ESI-09 is a specific exchange protein directly activated by cAMP (EPAC) inhibitor with IC50 of 3.2 μM and 1.4 μM for EPAC1 and EPAC2, respectively.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 32 | In Stock |
|
| 5MG | 50 | In Stock |
|
| 10MG | 80 | In Stock |
|
| 25MG | 159 | In Stock |
|
| 50MG | 288 | In Stock |
|
| 100MG | 434 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameESI-09
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NoteResearch use only, not for human use.
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Brief DescriptionESI-09 is a specific exchange protein directly activated by cAMP (EPAC) inhibitor with IC50 of 3.2 μM and 1.4 μM for EPAC1 and EPAC2, respectively.
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DescriptionESI-09 is a specific exchange protein directly activated by cAMP (EPAC) inhibitor with IC50 of 3.2 μM and 1.4 μM for EPAC1 and EPAC2, respectively, >100-fold selectivity over PKA.
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In Vitro——
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In Vivo——
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SynonymsESI09 | ESI 09 | ESI-09
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PathwayGPCR/G Protein
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TargetcAMP
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RecptorEPAC1| EPAC2
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number263707-16-0
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Formula Weight330.77
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Molecular FormulaC16H15ClN4O2
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Purity>98% (HPLC)
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SolubilityEthanol: 20 mg/mL warmed (60.46 mM); DMSO: 66 mg/mL (199.53 mM)
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SMILESN#C/C(C(C1=NOC(C(C)(C)C)=C1)=O)=N\NC2=CC=CC(Cl)=C2
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Chemical Name(E)-2-(5-(tert-butyl)isoxazol-3-yl)-N'-(3-chlorophenyl)-2-oxoacetohydrazonoyl cyanide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Almahariq M , et al. Mol Pharmacol. 2013, 83(1), 122-128.
2. Gong B, et al. Proc natl Acad Sci U S A. 2013, 110(48), 19615-19620.
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