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Home - Products - MAPK/ERK Signaling - ERK - ERK5-IN-2

ERK5-IN-2

CAS No. 1888305-96-1

ERK5-IN-2 ( —— )

Catalog No. M20408 CAS No. 1888305-96-1

ERK5-IN-2 is an orally active sub-micromolar selective ERK5 inhibitor with IC50s of 0.82 μM 3 μM for ERK5 and ERK5 MEF2D respectively.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    ERK5-IN-2
  • Note
    Research use only not for human use.
  • Brief Description
    ERK5-IN-2 is an orally active sub-micromolar selective ERK5 inhibitor with IC50s of 0.82 μM 3 μM for ERK5 and ERK5 MEF2D respectively.
  • Description
    ERK5-IN-2 is an orally active sub-micromolar selective ERK5 inhibitor with IC50s of 0.82 μM 3 μM for ERK5 and ERK5 MEF2D respectively.
  • Synonyms
    ——
  • Pathway
    MAPK/ERK Signaling
  • Target
    ERK
  • Recptor
    ERK5
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1888305-96-1
  • Formula Weight
    388.19
  • Molecular Formula
    C17H11BrFN3O2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    Fc1cccc(Br)c1C(=O)c1c[nH]c(c1)C(=O)Nc1cccnc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Myers SM Miller DC Molyneux L et al .Identification of a novel orally bioavailable ERK5 inhibitor with selectivity over p38α and BRD4[J].Eur J Med Chem. 2019 Sep 15;178:530-543.
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