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ER-000444793

CAS No. 792957-74-5

ER-000444793 ( —— )

Catalog No. M24791 CAS No. 792957-74-5

ER-000444793 is a potent mitochondrial permeability transition pore (mPTP) opening inhibitor and it also inhibits mPTP (IC50: 2.8?μM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 147 In Stock
10MG 222 In Stock
25MG 441 In Stock
50MG 644 In Stock
100MG 888 In Stock
500MG 1782 In Stock
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Biological Information

  • Product Name
    ER-000444793
  • Note
    Research use only, not for human use.
  • Brief Description
    ER-000444793 is a potent mitochondrial permeability transition pore (mPTP) opening inhibitor and it also inhibits mPTP (IC50: 2.8?μM).
  • Description
    ER-000444793 is a potent mitochondrial permeability transition pore (mPTP) opening inhibitor and it also inhibits mPTP (IC50: 2.8?μM).
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    mPTP
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    792957-74-5
  • Formula Weight
    354.4
  • Molecular Formula
    C23H18N2O2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:50 mg/mL (141.08 mM; Need ultrasonic)
  • SMILES
    O=C(NC1=C(CC2=CC=CC=C2)C=CC=C1)C(C3=CC=CC=C3N4)=CC4=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Briston T, et al. Identification of ER-000444793, a Cyclophilin D-independent inhibitor of mitochondrial permeability transition, using a high-throughput screen in cryopreserved mitochondria. Sci Rep. 2016 Nov 25;6:37798.
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