ER-000444793

CAS No. 792957-74-5

ER-000444793 ( —— )

Catalog No. M24791 CAS No. 792957-74-5

ER-000444793 is a potent mitochondrial permeability transition pore (mPTP) opening inhibitor and it also inhibits mPTP (IC50: 2.8?μM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 147 In Stock
10MG 222 In Stock
25MG 441 In Stock
50MG 644 In Stock
100MG 888 In Stock
500MG 1782 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    ER-000444793
  • Note
    Research use only, not for human use.
  • Brief Description
    ER-000444793 is a potent mitochondrial permeability transition pore (mPTP) opening inhibitor and it also inhibits mPTP (IC50: 2.8?μM).
  • Description
    ER-000444793 is a potent mitochondrial permeability transition pore (mPTP) opening inhibitor and it also inhibits mPTP (IC50: 2.8?μM).
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    mPTP
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    792957-74-5
  • Formula Weight
    354.4
  • Molecular Formula
    C23H18N2O2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:50 mg/mL (141.08 mM; Need ultrasonic)
  • SMILES
    O=C(NC1=C(CC2=CC=CC=C2)C=CC=C1)C(C3=CC=CC=C3N4)=CC4=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Briston T, et al. Identification of ER-000444793, a Cyclophilin D-independent inhibitor of mitochondrial permeability transition, using a high-throughput screen in cryopreserved mitochondria. Sci Rep. 2016 Nov 25;6:37798.
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