ELQ-300

CAS No. 1354745-52-0

ELQ-300( —— )

Catalog No. M20214 CAS No. 1354745-52-0

ELQ-300 is bioavailable antimalarial agent acts as an inhibitor of the reductive (Qi) site of the cytochrome bc1 complex (cyt bc1).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 110 In Stock
10MG 177 In Stock
25MG 357 In Stock
50MG 530 In Stock
100MG 759 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    ELQ-300
  • Note
    Research use only, not for human use.
  • Brief Description
    ELQ-300 is bioavailable antimalarial agent acts as an inhibitor of the reductive (Qi) site of the cytochrome bc1 complex (cyt bc1).
  • Description
    ELQ-300 is bioavailable antimalarial agent acts as an inhibitor of the reductive (Qi) site of the cytochrome bc1 complex (cyt bc1).
  • Synonyms
    ——
  • Pathway
    Microbiology/Virology
  • Target
    Parasite
  • Recptor
    Parasite
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1354745-52-0
  • Formula Weight
    475.85
  • Molecular Formula
    C24H17ClF3NO4
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:15.62 mg/mL?(32.83 mM)
  • SMILES
    COc1cc2[nH]c(C)c(-c3ccc(Oc4ccc(OC(F)(F)F)cc4)cc3)c(=O)c2cc1Cl
  • Chemical Name
    6-Chloro-7-methoxy-2-methyl-3-{4-[4-(trifluoromethoxy)phenoxy]phenyl}quinolin-4(1H)-one

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Stickles AM et al. Subtle changes in endochin-like quinolone structure alter the site of inhibition within the cytochrome bc1 complex of Plasmodium falciparum. Antimicrob Agents Chemother. 2015 Apr;59(4):1977-82.
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