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ELOVL6-IN-1

CAS No. 1185736-98-4

ELOVL6-IN-1 ( —— )

Catalog No. M23355 CAS No. 1185736-98-4

ELOVL6-IN-1 is a potent, orally active and selective?ELOVL6?inhibitor. ELOVL6-IN-1 dose-dependently inhibits mouse?ELOVL6?activities.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    ELOVL6-IN-1
  • Note
    Research use only, not for human use.
  • Brief Description
    ELOVL6-IN-1 is a potent, orally active and selective?ELOVL6?inhibitor. ELOVL6-IN-1 dose-dependently inhibits mouse?ELOVL6?activities.
  • Description
    ELOVL6-IN-1 is a potent, orally active and selective?ELOVL6?inhibitor. ELOVL6-IN-1 dose-dependently inhibits mouse?ELOVL6?activities, with an?IC50?value of 0.350 μM. ELOVL6-IN-1 inhibits?ELOVL6?in a noncompetitive manner for malonyl-CoA (Ki=994 nM) and palmitoyl-CoA[1].
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ELOVL6
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1185736-98-4
  • Formula Weight
    495.5
  • Molecular Formula
    C27H24F3N3O3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:45 mg/mL?(90.82 mM;?Need ultrasonic)
  • SMILES
    O=C1N(C2=CC=CC=C2)C3=C(C(C(C)(C)CC3)=O)C1(C4=C(C)NN(C5=CC=CC=C5)C4=O)C(F)(F)F
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Shimamura K, et al. 5,5-Dimethyl-3-(5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-1-phenyl-3-(trifluoromethyl)-3,5,6,7-tetrahydro-1H-indole-2,4-dione, a potent inhibitor for mammalian elongase of long-chain fatty acids family 6: examination of its potential utility as a pharmacological tool. J Pharmacol Exp Ther. 2009;330(1):249-256.
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