ELOVL1-IN-1
CAS No. 2227482-41-7
ELOVL1-IN-1 ( 1-(2-Fluorophenyl)-N-(1-(2-fluoropyridin-4-YL)-1H-pyrazol-3-YL)cyclopropane-1-carboxamide )
Catalog No. M28774 CAS No. 2227482-41-7
ELOVL1-IN-1 is an ELOVL1 inhibitor. ELOVL1-IN-1 can reduce the levels of very long chain fatty acids. ELOVL1-IN-1 can be used in the study of adrenoleukodystrophy (ALD).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 372 | Get Quote |
|
10MG | 556 | Get Quote |
|
25MG | 887 | Get Quote |
|
50MG | 1197 | Get Quote |
|
100MG | 1611 | Get Quote |
|
500MG | 3231 | Get Quote |
|
1G | Get Quote | Get Quote |
|
Biological Information
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Product NameELOVL1-IN-1
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NoteResearch use only, not for human use.
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Brief DescriptionELOVL1-IN-1 is an ELOVL1 inhibitor. ELOVL1-IN-1 can reduce the levels of very long chain fatty acids. ELOVL1-IN-1 can be used in the study of adrenoleukodystrophy (ALD).
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DescriptionELOVL1-IN-1 is an ELOVL1 inhibitor. ELOVL1-IN-1 can reduce the levels of very long chain fatty acids. ELOVL1-IN-1 can be used in the study of adrenoleukodystrophy (ALD).(In Vitro):Administration of 1 nM-10 μM ELOVL1-IN-1 for 48 h reduces the level of VLCFA, lysophosphatidylcholine (LPC) in adrenoleukodystrophy (ALD) patient fibroblasts and healthy human fibroblasts, ALD patient B‐lymphocytes, and human microglia.(In Vivo):Oral dministration of ELOVL1-IN-1 reduces of a VLCFA level, specifically C26:0 LPC level in blood of ABCD1 knockout mice (0.5-64 mg/kg; 28 days), wild‐type (WT) rats (30-300 mg/kg; 7 days), and cynomolgous monkeys (30 mg/kg; 7 days).
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Synonyms1-(2-Fluorophenyl)-N-(1-(2-fluoropyridin-4-YL)-1H-pyrazol-3-YL)cyclopropane-1-carboxamide
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PathwayOthers
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TargetOther Targets
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RecptorAhR
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Research Area——
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Indication——
Chemical Information
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CAS Number2227482-41-7
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Formula Weight340.3
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Molecular FormulaC18H14F2N4O
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C(C1(CC1)c(cccc1)c1F)Nc(cc1)nn1-c1cc(F)ncc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Current Patent Assignee: MAGENTA THERAPEUTICS INC - WO2020/51207, 2020, A2
molnova catalog
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