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EGTA-AM

CAS No. 99590-86-0

EGTA-AM( —— )

Catalog No. M33213 CAS No. 99590-86-0

EGTA-AM (EGTA Acetoxymethyl ester) is a calcium chelator, a metabolic biomarker of early-onset preeclampsia and late-onset preeclampsia.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    EGTA-AM
  • Note
    Research use only, not for human use.
  • Brief Description
    EGTA-AM (EGTA Acetoxymethyl ester) is a calcium chelator, a metabolic biomarker of early-onset preeclampsia and late-onset preeclampsia.
  • Description
    EGTA-?AM is a membrane permeable form of EGTA, can be passively loaded into cells to generate intracellular EGTA; EGTA-?AM is also a Ca2+ chelator with slow chelating dynamics.
  • In Vitro
    EGTA-AM (50 μM) markedly reduces the asynchronous excitatory postsynaptic currents (aEPSC) to 58.9 ± 8.1% of the control level, but only reduces the synchronous excitatory postsynaptic currents (EPSCs), measured as charge transfer produced by the stimulation train.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    99590-86-0
  • Formula Weight
    668.6
  • Molecular Formula
    C26H40N2O18
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (149.57 mM; Ultrasonic (<60°C)
  • SMILES
    CC(=O)OCOC(=O)CN(CCOCCOCCN(CC(=O)OCOC(C)=O)CC(=O)OCOC(C)=O)CC(=O)OCOC(C)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Li MJ, et al. Cholinergic and glutamatergic transmission at synapses between pedunculopotine tegmental nucleus axonal terminals and A7 catecholamine cell group noradrenergic neurons in the rat. Neuropharmacology. 2016 Nov;110(Pt A):237-50?
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