EACC

CAS No. 864941-31-1

EACC( —— )

Catalog No. M26188 CAS No. 864941-31-1

EACC selectively inhibits the translocation of autophagosome-specific SNARE Stx17 thereby blocking autophagosome-lysosome fusion.?

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 177 Get Quote
10MG 314 Get Quote
25MG 536 Get Quote
50MG 764 Get Quote
100MG 1053 Get Quote
500MG 2115 Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    EACC
  • Note
    Research use only, not for human use.
  • Brief Description
    EACC selectively inhibits the translocation of autophagosome-specific SNARE Stx17 thereby blocking autophagosome-lysosome fusion.?
  • Description
    EACC selectively inhibits the translocation of autophagosome-specific SNARE Stx17 thereby blocking autophagosome-lysosome fusion.?EACC is a reversible autophagy inhibitor.(In Vitro):EACC inhibits autophagy by preventing SNARE Stx17 loading on autophagosomes. EACC does not affect RABs, tethers, and lysosomal SNARE but prevents their interaction with LC3 and Stx17.EACC blocks autophagosome-lysosome fusion but does not affect endo-lysosomal function.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Autophagy
  • Target
    Autophagy
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    864941-31-1
  • Formula Weight
    369.37
  • Molecular Formula
    C13H11N3O6S2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 16.88 mg/mL (45.70 mM)
  • SMILES
    CCOC(=O)NC(=O)c1ccsc1NC(=O)c1ccc(s1)[N+]([O-])=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Yue L, Liu YJ. Mechanism of AMPPD Chemiluminescence in a Different Voice. J Chem Theory Comput. 2013 May 14;9(5):2300-12.
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