EACC

Research use only, not for human use.

EACC selectively inhibits the translocation of autophagosome-specific SNARE Stx17 thereby blocking autophagosome-lysosome fusion.?

EACC selectively inhibits the translocation of autophagosome-specific SNARE Stx17 thereby blocking autophagosome-lysosome fusion.?EACC is a reversible autophagy inhibitor.(In Vitro):EACC inhibits autophagy by preventing SNARE Stx17 loading on autophagosomes. EACC does not affect RABs, tethers, and lysosomal SNARE but prevents their interaction with LC3 and Stx17.EACC blocks autophagosome-lysosome fusion but does not affect endo-lysosomal function.

——

——

——

Autophagy

Autophagy

——

——

——

864941-31-1

369.37

C13H11N3O6S2

>98% (HPLC)

In Vitro:?DMSO : 16.88 mg/mL (45.70 mM)

CCOC(=O)NC(=O)c1ccsc1NC(=O)c1ccc(s1)[N+]([O-])=O

——

(-20℃)

With Ice Pack

≥ 2 years