E7820

CAS No. 289483-69-8

E7820 ( E7820; E-7820; E 7820 )

Catalog No. M17466 CAS No. 289483-69-8

E7820 is an angiogenesis inhibitor by suppressing integrin a2 (a cell adhesion molecule expressed on endothelial cells).

Purity : 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 40 In Stock
5MG 57 In Stock
10MG 72 In Stock
25MG 132 In Stock
50MG 200 In Stock
100MG 321 In Stock
200MG 476 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    E7820
  • Note
    Research use only, not for human use.
  • Brief Description
    E7820 is an angiogenesis inhibitor by suppressing integrin a2 (a cell adhesion molecule expressed on endothelial cells).
  • Description
    E7820 is a small molecule and aromatic sulfonamide derivative with potential antiangiogenic and antitumor activities. E7820 inhibits angiogenesis by suppressing integrin alpha 2, a cell adhesion molecule expressed on endothelial cells. Inhibition of integrin alpha 2 leads to an inhibition of cell-cell interactions, endothelial cell-matrix interactions, vascular endothelial cell proliferation and angiogenesis. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus).
  • Synonyms
    E7820; E-7820; E 7820
  • Pathway
    Endocrinology/Hormones
  • Target
    AChR
  • Recptor
    integrin a2
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    289483-69-8
  • Formula Weight
    336.37
  • Molecular Formula
    C17H12N4O2S
  • Purity
    98%
  • Solubility
    DMSO : ≥ 33 mg/mL; 98.11 mM
  • SMILES
    Cc1ccc(NS(=O)(=O)c2cccc(c2)C#N)c2[nH]cc(C#N)c12
  • Chemical Name
    N-(3-cyano-4-methyl-1H-indol-7-yl)-3-cyanobenzene-sulfonamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Ito K, Semba T, Uenaka T, et al. Cancer science, 2014, 105(8): 1023-1031.
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