E7820
CAS No. 289483-69-8
E7820 ( E7820; E-7820; E 7820 )
Catalog No. M17466 CAS No. 289483-69-8
E7820 is an angiogenesis inhibitor by suppressing integrin a2 (a cell adhesion molecule expressed on endothelial cells).
Purity : 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
2MG | 40 | In Stock |
|
5MG | 57 | In Stock |
|
10MG | 72 | In Stock |
|
25MG | 132 | In Stock |
|
50MG | 200 | In Stock |
|
100MG | 321 | In Stock |
|
200MG | 476 | In Stock |
|
500MG | Get Quote | In Stock |
|
1G | Get Quote | In Stock |
|
Biological Information
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Product NameE7820
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NoteResearch use only, not for human use.
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Brief DescriptionE7820 is an angiogenesis inhibitor by suppressing integrin a2 (a cell adhesion molecule expressed on endothelial cells).
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DescriptionE7820 is a small molecule and aromatic sulfonamide derivative with potential antiangiogenic and antitumor activities. E7820 inhibits angiogenesis by suppressing integrin alpha 2, a cell adhesion molecule expressed on endothelial cells. Inhibition of integrin alpha 2 leads to an inhibition of cell-cell interactions, endothelial cell-matrix interactions, vascular endothelial cell proliferation and angiogenesis. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus).
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SynonymsE7820; E-7820; E 7820
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PathwayEndocrinology/Hormones
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TargetAChR
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Recptorintegrin a2
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number289483-69-8
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Formula Weight336.37
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Molecular FormulaC17H12N4O2S
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Purity98%
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SolubilityDMSO : ≥ 33 mg/mL; 98.11 mM
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SMILESCc1ccc(NS(=O)(=O)c2cccc(c2)C#N)c2[nH]cc(C#N)c12
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Chemical NameN-(3-cyano-4-methyl-1H-indol-7-yl)-3-cyanobenzene-sulfonamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Ito K, Semba T, Uenaka T, et al. Cancer science, 2014, 105(8): 1023-1031.
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