E7820
CAS No. 289483-69-8
E7820 ( E7820; E-7820; E 7820 )
Catalog No. M17466 CAS No. 289483-69-8
E7820 is an angiogenesis inhibitor by suppressing integrin a2 (a cell adhesion molecule expressed on endothelial cells).
Purity : 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
2MG | 40 | In Stock |
|
5MG | 57 | In Stock |
|
10MG | 72 | In Stock |
|
25MG | 132 | In Stock |
|
50MG | 200 | In Stock |
|
100MG | 321 | In Stock |
|
200MG | 476 | In Stock |
|
500MG | Get Quote | In Stock |
|
1G | Get Quote | In Stock |
|
Biological Information
-
Product NameE7820
-
NoteResearch use only, not for human use.
-
Brief DescriptionE7820 is an angiogenesis inhibitor by suppressing integrin a2 (a cell adhesion molecule expressed on endothelial cells).
-
DescriptionE7820 is a small molecule and aromatic sulfonamide derivative with potential antiangiogenic and antitumor activities. E7820 inhibits angiogenesis by suppressing integrin alpha 2, a cell adhesion molecule expressed on endothelial cells. Inhibition of integrin alpha 2 leads to an inhibition of cell-cell interactions, endothelial cell-matrix interactions, vascular endothelial cell proliferation and angiogenesis. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus).
-
SynonymsE7820; E-7820; E 7820
-
PathwayEndocrinology/Hormones
-
TargetAChR
-
Recptorintegrin a2
-
Research AreaCancer
-
Indication——
Chemical Information
-
CAS Number289483-69-8
-
Formula Weight336.37
-
Molecular FormulaC17H12N4O2S
-
Purity98%
-
SolubilityDMSO : ≥ 33 mg/mL; 98.11 mM
-
SMILESCc1ccc(NS(=O)(=O)c2cccc(c2)C#N)c2[nH]cc(C#N)c12
-
Chemical NameN-(3-cyano-4-methyl-1H-indol-7-yl)-3-cyanobenzene-sulfonamide
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Ito K, Semba T, Uenaka T, et al. Cancer science, 2014, 105(8): 1023-1031.
molnova catalog
related products
-
Sitogluside
Eleutheroside A (Daucosterol) has proliferation-enhancing activity, may be involved in the IGF1-AKT pathway.
-
Adenine
Adenine is a purine derivative and a nucleobase with a variety of roles in biochemistry.
-
Neostigmine bromide
Neostigmine bromide(Prostigmin) is a reversible acetylcholinesterase inhibitor and a parasympatho-mimetic.