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Droxicainide

CAS No. 78289-26-6

Droxicainide( —— )

Catalog No. M26178 CAS No. 78289-26-6

Droxicainide is an antiarrhythmic agent.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Droxicainide
  • Note
    Research use only, not for human use.
  • Brief Description
    Droxicainide is an antiarrhythmic agent.
  • Description
    Droxicainide is an antiarrhythmic agent.(In Vivo):In coronary artery occlusion studies, Droxicainide reduced the progression of hypoperfusion to necrosis and reduced the infarct size in dogs.Droxicainide reduces ansa node, atrioventricular excitability and contractility, and increases intractable studies on spontaneous beating atrium, electrical stimulation atrium and isolated papillary muscles in rats.
  • In Vitro
    ——
  • In Vivo
    In coronary artery occlusion study, Droxicainide reduces hypoperfused area that evolves to necrosis, and reduces the infarct size in dogs. Droxicainide decreases the sinus node, atrial and ventricular excitability and contractile force and increases the refractoriness in the study of spontaneously beating atria, electrically stimulated atria and papillary muscles isolated from rats.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ER
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    78289-26-6
  • Formula Weight
    276.38
  • Molecular Formula
    C16H24N2O2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    Cc1cccc(C)c1NC(=O)C1CCCCN1CCO
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Ohta, K., et al. Promising core structure for nuclear receptor ligands:Design and synthesis of novel estrogen receptor ligands based on diphenylamine skeleton. Bioorganic & Medicinal Chemistry Letters.2008;18(18), 5050–5053.
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