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Disulfamide
CAS No. 671-88-5
Disulfamide( —— )
Catalog No. M35441 CAS No. 671-88-5
Disulfamide is an orally active carbonic anhydrase inhibitor with an IC50 value of 0.07 μM. Disulfamide has a diuretic effect by inhibiting carbonic anhydrase and preventing the reabsorption of sodium and bicarbonate in the proximal convoluted tubules.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 160 | Get Quote |
|
| 5MG | 246 | Get Quote |
|
| 10MG | 377 | Get Quote |
|
| 25MG | 713 | Get Quote |
|
| 50MG | 975 | Get Quote |
|
| 100MG | 1287 | Get Quote |
|
| 500MG | 2592 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameDisulfamide
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NoteResearch use only, not for human use.
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Brief DescriptionDisulfamide is an orally active carbonic anhydrase inhibitor with an IC50 value of 0.07 μM. Disulfamide has a diuretic effect by inhibiting carbonic anhydrase and preventing the reabsorption of sodium and bicarbonate in the proximal convoluted tubules.
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DescriptionDisulfamide, an orally active diuretic, is a carbonic anhydrase inhibitor with the IC50 value of 0.07 μM. Disulfamide leads to diuresis by inhibiting carbonic anhydrase and preventing the reabsorption of sodium and bicarbonate in the proximal tubule.
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In Vitro——
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In VivoDisulfamide (intraperitoneal injection, 200 mg/kg, once) has potential blood glucose raising properties in male Wistar rats.Animal Model:Male Wistar rats weighing between 200-300 g Dosage:200 mg/kg Administration: Intraperitoneal injection; once Result:Resulted in elevated blood sugar levels from an initial blood glucose concentration of 143.1 mg/100 mL to a one hour later final concentration of 194.6 mg/100 mL, an increase of 36%.
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Synonyms——
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PathwayMembrane Transporter/Ion Channel
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TargetCarbonic Anhydrase
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RecptorCarbonic Anhydrase
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Research Area——
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Indication——
Chemical Information
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CAS Number671-88-5
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Formula Weight284.74
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Molecular FormulaC7H9ClN2O4S2
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Purity>98% (HPLC)
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Solubility——
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SMILESS(N)(=O)(=O)C1=CC(S(N)(=O)=O)=C(Cl)C=C1C
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. CT Supuran, et al. Carbonic anhydrase inhibitors: Synthesis and inhibitory properties of 1,3,4-thiadiazole-2,5-bissulfonamide. European Journal of Medicinal Chemistry,Volume 31, Issue 11, 1996, Pages 843-846.
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