Diosgenin ( —— )

Catalog No. M18693 CAS No. 512-04-9

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Product Name

Diosgenin
Note

Research use only, not for human use.
Brief Description

Diosgenin is a spirostan found in DIOSCOREA and other plants. It has favorable effects in the improvement of diabetes and regulation of lipid metabolism.
Description

Diosgenin, a steroid sapogenin, is the product of hydrolysis by acids, strong bases, or enzymes of saponins, extracted from the tubers of Dioscorea wild yam, such as the Kokoro. The sugar-free (aglycone) diosgenin is used for the commercial synthesis of cortisone, pregnenolone, progesterone, and other steroid products. Diosgenin is the precursor for the semisynthesis of progesterone which in turn was used in early combined oral contraceptive pills. The unmodified steroid has estrogenic activity and can reduce the level of serum cholesterol.
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

Others
Research Area

Metabolic Disease
Indication

——

CAS Number

512-04-9
Formula Weight

414.63
Molecular Formula

C27H42O3
Purity

98%
Solubility

Ethanol : 6.67 mg/mL 16.09 mM; DMSO : < 1 mg/mL
SMILES

O1[C@@H]2[C@H]([C@@H]([C@@]31CC[C@@H](CO3)C)C)[C@@]1([C@@H](C2)[C@H]2[C@H](CC1)[C@@]1(C(=CC2)C[C@H](CC1)O)C)C
Chemical Name

(3β,25R)-spirost-5-en-3-ol

1. Wu L, et al. Biol Reprod. 2015 Jan;92(1):24.

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