Dimethylacrylshikonin

CAS No. 24502-79-2

Dimethylacrylshikonin( —— )

Catalog No. M18302 CAS No. 24502-79-2

Dimethylacrylshikonin is a promising agent for developing an improved strategy for radiotherapy against tumors.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Dimethylacrylshikonin
  • Note
    Research use only, not for human use.
  • Brief Description
    Dimethylacrylshikonin is a promising agent for developing an improved strategy for radiotherapy against tumors.
  • Description
    Dimethylacrylshikonin is a promising agent for developing an improved strategy for radiotherapy against tumors. (a) Injection of Dimethylacrylshikonin combined with IR treatment significantly suppressed tumor growth of the HCT-116 xenograft. (b) Dimethylacrylshikonin significantly suppressed the growth of H(22) transplantable hepatoma, and induced the activation of caspase-3 . (c) Dimethylacrylshikonin inhibited growth of gastric cancer SGC-791 cells by inducing ERK signaling pathway. Dimethylacrylshikonin inhibits the proliferation of MCF-7 cells in vitro by inducing apoptosis through the downregulation of Bcl-2, upregulation of Bax and partial inactivation of the NF-κB pathway.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Antioxidant
  • Recptor
    ERK
  • Research Area
    Others-Field
  • Indication
    ——

Chemical Information

  • CAS Number
    24502-79-2
  • Formula Weight
    370.4
  • Molecular Formula
    C21H22O6
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 12.5 mg/mL (33.75 mM)
  • SMILES
    CC(=CCC(C1=CC(=O)C2=C(C=CC(=C2C1=O)O)O)OC(=O)C=C(C)C)C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

molnova catalog
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