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Diclone
CAS No. 117-80-6
Diclone ( Phygon;23-Dichloro-14-naphthoquinone;Sanquinon )
Catalog No. M19469 CAS No. 117-80-6
2 ?3-?Dichloro-?1 ?4-?naphthoquinone is an inhibitor of Itch a HECT domain-E3 ligase. It is also used in pesticide formulations.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameDiclone
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NoteResearch use only not for human use.
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Brief Description2 ?3-?Dichloro-?1 ?4-?naphthoquinone is an inhibitor of Itch a HECT domain-E3 ligase. It is also used in pesticide formulations.
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Description2 ?3-?Dichloro-?1 ?4-?naphthoquinone is an inhibitor of Itch a HECT domain-E3 ligase. It is also used in pesticide formulations.
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SynonymsPhygon;23-Dichloro-14-naphthoquinone;Sanquinon
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PathwayPROTACs
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TargetE3 Ligase Ligand
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RecptorItch
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Research Area——
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Indication——
Chemical Information
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CAS Number117-80-6
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Formula Weight227.04
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Molecular FormulaC10H4Cl2O2
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Purity>98% (HPLC)
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SolubilityDMSO:10 mM
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SMILESClC1=C(Cl)C(=O)c2ccccc2C1=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Liu Y M et al. 14-Naphthoquinones as inhibitors of Itch a HECT domain-E3 ligase and tumor growth suppressors in multiple myeloma.[J]. European Journal of Medicinal Chemistry 2017 140:84.
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