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Dianemycin

CAS No. 35865-33-9

Dianemycin ( Nanchangmycin (free acid) )

Catalog No. M21964 CAS No. 35865-33-9

Dianemycin is a broad spectrum polyether antibiotic, inhibits gram-positive bacteria.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Dianemycin
  • Note
    Research use only, not for human use.
  • Brief Description
    Dianemycin is a broad spectrum polyether antibiotic, inhibits gram-positive bacteria.
  • Description
    Dianemycin is a broad spectrum polyether antibiotic, inhibits gram-positive bacteria.?Nanchangmycin is a broad spectrum antiviral active against Zika virus
  • Synonyms
    Nanchangmycin (free acid)
  • Pathway
    GPCR/G Protein
  • Target
    Antibacterial
  • Recptor
    Bacterial
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    35865-33-9
  • Formula Weight
    867.11
  • Molecular Formula
    C47H78O14
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:150 mg/ml(172.99 mM; Need ultrasonic)
  • SMILES
    [H][C@@]1(C[C@H](O[C@@H]2CC[C@H](OC)[C@@H](C)O2)[C@@H](C)[C@@]2(O[C@H](C[C@@H]2C)[C@@]2([H])O[C@@](O)(CO)[C@H](C)C[C@@H]2C)O1)[C@]1(C)CC[C@]2(C[C@H](O)[C@@H](C)[C@]([H])(O2)[C@@H](C)\C=C(/C)C(=O)[C@H](C)C[C@H](C)C(O)=O)O1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Hamill R L , Hoenh M M , Pittenger G E , et al. DIANEMYCIN, AN ANTIBIOTIC OF THE GROUP AFFECTING ION TRANSPORT[J]. The Journal of Antibiotics, 1969, 22(4):161-164.2. Rausch K, et al. Screening Bioactives Reveals Nanchangmycin as a Broad Spectrum Antiviral Active against Zika Virus. Cell Rep. 2017 Jan 17;18(3):804-815.3. Liu T, et al. Mechanism of thioesterase-catalyzed chain release in the biosynthesis of the polyether antibiotic Nanchangmycin. Chem Biol. 2008 May;15(5):449-58.
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