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Dexrazoxane
CAS No. 24584-09-6
Dexrazoxane( ICRF-187 | NSC-169780 )
Catalog No. M13714 CAS No. 24584-09-6
A derivative of EDTA that chelates iron and reduces the number of metal ions complexed with anthracycline and, consequently, decrease the formation of superoxide radicals.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 25MG | 35 | In Stock |
|
| 50MG | 51 | In Stock |
|
| 100MG | 73 | In Stock |
|
| 500MG | 180 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameDexrazoxane
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NoteResearch use only, not for human use.
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Brief DescriptionA derivative of EDTA that chelates iron and reduces the number of metal ions complexed with anthracycline and, consequently, decrease the formation of superoxide radicals.
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DescriptionA derivative of EDTA that chelates iron and reduces the number of metal ions complexed with anthracycline and, consequently, decrease the formation of superoxide radicals; protects the heart against the cardiotoxic side effects of chemotherapeutic drugs.Chemotherapeutic Agents Approved
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In Vitro——
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In Vivo——
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SynonymsICRF-187 | NSC-169780
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PathwayOthers
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TargetOther Targets
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RecptorOther Targets
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Research AreaCancer
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IndicationChemotherapeutic
Chemical Information
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CAS Number24584-09-6
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Formula Weight268.2691
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Molecular FormulaC11H16N4O4
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Purity>98% (HPLC)
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Solubility10 mM in DMSO
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SMILESC[C@H](N(C1)CC(NC1=O)=O)CN(C2)CC(NC2=O)=O
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Chemical Name2,6-Piperazinedione, 4,4'-[(1S)-1-methyl-1,2-ethanediyl]bis-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Lipshultz SE, et al. N Engl J Med. 2004 Jul 8;351(2):145-53.
2. Bjelogrlic SK, et al. Exp Biol Med (Maywood). 2007 Dec;232(11):1414-24.
3. Jones RL, et al. Expert Rev Cardiovasc Ther. 2008 Nov;6(10):1311-7.
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