Desoxypeganine
CAS No. 495-59-0
Desoxypeganine( Deoxypeganine )
Catalog No. M24453 CAS No. 495-59-0
Desoxypeganine is an inhibitor of cholinesterase. It acting preferentially on butyrylcholinesterase, and as a selective inhibitor of monoamine oxidase A but not monoamine oxidase B.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameDesoxypeganine
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NoteResearch use only, not for human use.
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Brief DescriptionDesoxypeganine is an inhibitor of cholinesterase. It acting preferentially on butyrylcholinesterase, and as a selective inhibitor of monoamine oxidase A but not monoamine oxidase B.
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DescriptionDesoxypeganine is an inhibitor of cholinesterase. It acting preferentially on butyrylcholinesterase, and as a selective inhibitor of monoamine oxidase A but not monoamine oxidase B.Desoxypeganine is being developed for its potential utility in the pharmacological treatment of alcohol abuse to reduce craving and depression in alcohol abusers,?and might also be useful as a smoking cessation aid.
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In Vitro——
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In VivoAnimal Model:Female Alko alcohol (AA) rats (Thirty eight adult) Dosage:10, 20, 30 mg/kg Administration:Gavage, once daily in a volume of 10 ml/kg at 6:00 pm, for 16 days Result:Abolished ethanol preference.
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SynonymsDeoxypeganine
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PathwayMetabolic Enzyme/Protease
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TargetAChE
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Recptorcholinesterase
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Research Area——
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Indication——
Chemical Information
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CAS Number495-59-0
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Formula Weight172.23
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Molecular FormulaC11H12N2
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Purity>98% (HPLC)
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SolubilityDMSO:10 mM
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SMILESC1CC2=NC3=CC=CC=C3CN2C1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Herraiz T , H Guillén, VJ Arán, et al. Identification, occurrence and activity of quinazoline alkaloids in Peganum harmala[J]. Food and Chemical Toxicology, 2017, 103:261.
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