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Deferasirox

CAS No. 201530-41-8

Deferasirox ( ICL670A )

Catalog No. M13141 CAS No. 201530-41-8

An oral iron chelator that used to reduce chronic iron overload; also induces apoptosis in myeloid leukemia cells by targeting caspase.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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25MG 71 In Stock
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Biological Information

  • Product Name
    Deferasirox
  • Note
    Research use only, not for human use.
  • Brief Description
    An oral iron chelator that used to reduce chronic iron overload; also induces apoptosis in myeloid leukemia cells by targeting caspase.
  • Description
    An oral iron chelator that used to reduce chronic iron overload; also induces apoptosis in myeloid leukemia cells by targeting caspase.
  • Synonyms
    ICL670A
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    iron
  • Research Area
    Other Indications
  • Indication
    Other Disease

Chemical Information

  • CAS Number
    201530-41-8
  • Formula Weight
    373.36
  • Molecular Formula
    C21H15N3O4
  • Purity
    >98% (HPLC)
  • Solubility
    10 mM in DMSO
  • SMILES
    O=C(O)C1=CC=C(N2N=C(C3=CC=CC=C3O)N=C2C4=CC=CC=C4O)C=C1
  • Chemical Name
    Benzoic acid, 4-[3,5-bis(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl]-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Sobbe A, et al. J Gastroenterol Hepatol. 2015 Mar;30(3):638-45.
2. Kim JL, et al. Acta Haematol. 2011;126(4):241-5.
3. Lee DH, et al. Exp Hematol. 2013 Jun;41(6):539-46.
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