Dacarbazine
CAS No. 4342-03-4
Dacarbazine ( NCI C04717; NSC 45388 )
Catalog No. M14481 CAS No. 4342-03-4
Dacarbazine(DTIC-Dome) is an antineoplastic chemotherapy drug used in the treatment of various Ys, among them malignant melanoma, Hodgkin lymphoma, sarcoma, and islet cell carcinoma of the pancreas.
Purity : >98%(HPLC)
Size | Price / USD | Stock | Quantity |
50MG | 29 | In Stock |
|
100MG | 45 | In Stock |
|
200MG | 52 | In Stock |
|
1G | 87 | In Stock |
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Biological Information
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Product NameDacarbazine
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NoteResearch use only, not for human use.
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Brief DescriptionDacarbazine(DTIC-Dome) is an antineoplastic chemotherapy drug used in the treatment of various Ys, among them malignant melanoma, Hodgkin lymphoma, sarcoma, and islet cell carcinoma of the pancreas.
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DescriptionDacarbazine(DTIC-Dome) is an antineoplastic chemotherapy drug used in the treatment of various Ys, among them malignant melanoma, Hodgkin lymphoma, sarcoma, and islet cell carcinoma of the pancreas.
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SynonymsNCI C04717; NSC 45388
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PathwayCell Cycle/DNA Damage
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TargetDNA/RNA Synthesis
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RecptorDNA polymerase beta
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number4342-03-4
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Formula Weight182.18
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Molecular FormulaC6H10N6O
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Purity>98%(HPLC)
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SolubilityDMSO: 3 mg/mL (16.46 mM)
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SMILESO=C(C1=C(/N=N/N(C)C)NC=N1)N
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Chemical Name(E)-5-(3,3-dimethyltriaz-1-en-1-yl)-1H-imidazole-4-carboxamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Afobazole hydrochlor...
Fabomotizole HCl (CM346 HCl), an anxiolytic drug, produces anxiolytic and neuroprotective effects.
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NSAH?
NSAH is a nonnucleoside inhibitor of human ribonucleotide reductase (hRR).with cell-free IC50 of 32 μM and cell-based IC50 of ~250 nM, respectively.A unique nonnucleoside small-molecule hRR inhibitor, naphthyl salicylic acyl hydrazone (NSAH), using virtual screening, binding affinity, inhibition, and cell toxicity assays.?NSAH binds to hRRM1 with an apparent dissociation constant of 37 μM, and steady-state kinetics reveal a competitive mode of inhibition.?
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GSK3685032
GSK3685032 is a non-covalent and selective DNMT1 inhibitor(IC50 = 36 nM). The inhibitory effect is time-independent and reversible.