DW14800

CAS No. 2243709-60-4

DW14800( —— )

Catalog No. M26185 CAS No. 2243709-60-4

DW14800 is an inhibitor of PRMT5 (IC50 = 17 nM), enhances the transcription of HNF4α, and reduces the level of H4R3me2s.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 119 Get Quote
5MG 205 Get Quote
10MG 357 Get Quote
25MG 680 Get Quote
50MG 897 Get Quote
100MG 1341 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    DW14800
  • Note
    Research use only, not for human use.
  • Brief Description
    DW14800 is an inhibitor of PRMT5 (IC50 = 17 nM), enhances the transcription of HNF4α, and reduces the level of H4R3me2s.
  • Description
    DW14800 is an inhibitor of PRMT5 (IC50 = 17 nM), enhances the transcription of HNF4α, and reduces the level of H4R3me2s.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Chromatin/Epigenetic
  • Target
    Histone Demethylase
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2243709-60-4
  • Formula Weight
    512.64
  • Molecular Formula
    C31H36N4O3
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (195.07 mM)
  • SMILES
    CN(C)c1ccc(cc1)C(=O)N1CCc2cc(ccc2C1)C(=O)NCC(O)CN1CCc2ccccc2C1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Aryal M, Pranatharthiharan P, Muriana PM. Optimization of a Microplate Assay for Generating Listeria Monocytogenes, E. Coli O157:H7, and Salmonella Biofilms and Enzymatic Recovery for Enumeration. Foods. 2019 Nov 2;8(11):541.
molnova catalog
related products
  • KDM5A-IN-1

    An inhibitor of histone demethylase.

  • SGC-iMLLT

    SGC-iMLLT is a potent and selective MLLT1/3-histone interactions inhibitor(IC50 = 0.26 μM),and is a first-in-class chemical probe displaying cellular target engagement of MLLT1(Kd = 0.129?μM) and MLLT3(Kd = 0.077?μM).

  • KDM4C-IN-1

    KDM4C-IN-1 is a selective and potent KDM4C inhibitor (IC50: 8 nM) with potential anticancer activity.KDM4C-IN-1 inhibits the growth of HepG2 and A549 cells, and can be used for the study of leukaemia.