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DO1

CAS No. 2581-69-3

DO1 ( Disperse Orange 1 )

Catalog No. M21106 CAS No. 2581-69-3

DO1 is an anti-amyloid agent which potently delays both seeded and non-seeded Aβ42 polymerization at substoichiometric concentrations.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    DO1
  • Note
    Research use only not for human use.
  • Brief Description
    DO1 is an anti-amyloid agent which potently delays both seeded and non-seeded Aβ42 polymerization at substoichiometric concentrations.
  • Description
    DO1 is an anti-amyloid agent which potently delays both seeded and non-seeded Aβ42 polymerization at substoichiometric concentrations.
  • Synonyms
    Disperse Orange 1
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2581-69-3
  • Formula Weight
    318.33
  • Molecular Formula
    C18H14N4O2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=[N+]([O-])c1ccc(N=Nc2ccc(Nc3ccccc3)cc2)cc1
  • Chemical Name
    4-((4-Nitrophenyl)diazenyl)-N-phenylaniline

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Boeddrich A Babila JT Wiglenda Tet al.The Anti-amyloid Compound DO1 Decreases Plaque Pathology and Neuroinflammation-Related Expression Changes in 5xFAD Transgenic Mice[J].Cell Chem Biol. 2019 Jan 17 ;26(1):109-120.e7.?
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