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DNS-pE2
CAS No. ——
DNS-pE2( —— )
Catalog No. M16974 CAS No. ——
DNS-pE2 is the first small molecule that can selectively label endogenous 3-phosphoglycerate dehydrogenase (PHGDH) from various mammalian cells.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameDNS-pE2
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NoteResearch use only, not for human use.
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Brief DescriptionDNS-pE2 is the first small molecule that can selectively label endogenous 3-phosphoglycerate dehydrogenase (PHGDH) from various mammalian cells.
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DescriptionDNS-pE2 is the first small molecule that can selectively label endogenous 3-phosphoglycerate dehydrogenase (PHGDH) from various mammalian cells; is highly fluorescent only upon irreversible covalent modification of PHGDH with an inhibitory property (in vitro Ki=7.4 uM).
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetFluorescent Dye
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RecptorFluorescent Dye
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Research Area——
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Indication——
Chemical Information
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CAS Number——
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Formula Weight285.361
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Molecular FormulaC16H15NO2S
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical NameN-methyl-N-(prop-2-yn-1-yl)-6-(vinylsulfonyl)naphthalen-2-amine
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Pan S, et al. Angew Chem Int Ed Engl. 2018 Jan 8;57(2):579-583.
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