DNDI-6148
CAS No. 2243909-59-1
DNDI-6148( —— )
Catalog No. M35150 CAS No. 2243909-59-1
DNDI-6148 has anti-experimental cutaneous leishmaniasis activity and can be used to study visceral leishmaniasis by inhibiting Leishmania protozoa cleavage and polyadenylation-specific factor (CPSF3) endonuclease.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 445 | Get Quote |
|
| 5MG | 686 | Get Quote |
|
| 10MG | 938 | Get Quote |
|
| 25MG | 1398 | Get Quote |
|
| 50MG | 1822 | Get Quote |
|
| 100MG | 2484 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameDNDI-6148
-
NoteResearch use only, not for human use.
-
Brief DescriptionDNDI-6148 has anti-experimental cutaneous leishmaniasis activity and can be used to study visceral leishmaniasis by inhibiting Leishmania protozoa cleavage and polyadenylation-specific factor (CPSF3) endonuclease.
-
DescriptionDNDI-6148 is a novel preclinical candidate for the research of visceral leishmaniasis.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayMicrobiology/Virology
-
TargetParasite
-
RecptorParasite
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2243909-59-1
-
Formula Weight335.13
-
Molecular FormulaC16H14BN5O3
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESO=C(NC1=CC=C2C(=C1)B(O)OC2)C=3N=NN(C4=NC=CC=C4)C3C
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Mowbray CE, et al. DNDI-6148: A Novel Benzoxaborole Preclinical Candidate for the Treatment of Visceral Leishmaniasis. J Med Chem. 2021 Nov 11;64(21):16159-16176. ?
molnova catalog
related products
-
GSK3186899
GSK3186899 is an inhibitor of Cdc2-related kinase 12 with an EC50 of 1.4 μM for L. donovani.
-
Dehydroemetine
Dehydroemetine is an effective antigenic insecticide, which is a synthetic analogue of Emetine dihydrochloride. It can be used to prevent and treat amoeba infections and diseases.
-
DDD85646
DDD85646 is an inhibitor of T. brucei N-myristoyltransferase with a Ki of 1.44 nM, an IC50 of 2 nM and an EC50 of 2 nM. The IC50 of hNMT is 4 nM.
Cart
sales@molnova.com