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DMU-212
CAS No. 134029-62-2
DMU-212 ( —— )
Catalog No. M28078 CAS No. 134029-62-2
DMU-212, a methylated form of Resveratrol, shows antimitotic, antiproliferative, and antioxidant activities. DMU-212 induces mitotic arrest through the activation of ERK1/2 protein and the promotion of apoptosis.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 27 | Get Quote |
|
| 5MG | 43 | Get Quote |
|
| 10MG | 72 | Get Quote |
|
| 25MG | 147 | Get Quote |
|
| 50MG | 259 | Get Quote |
|
| 100MG | 385 | Get Quote |
|
| 500MG | 872 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameDMU-212
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NoteResearch use only, not for human use.
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Brief DescriptionDMU-212, a methylated form of Resveratrol, shows antimitotic, antiproliferative, and antioxidant activities. DMU-212 induces mitotic arrest through the activation of ERK1/2 protein and the promotion of apoptosis.
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DescriptionDMU-212, a methylated form of Resveratrol, shows antimitotic, antiproliferative, and antioxidant activities. DMU-212 induces mitotic arrest through the activation of ERK1/2 protein and the promotion of apoptosis.(In Vitro):DMU-212 (0.3125-40 μM) inhibited the cellular proliferation of human melanoma cells at submicromolar or micromolar concentrations (IC50=0.5 μM, 0.5 μM, 1.25 μM, and 1.25 μM for A375, Bro, MeWo, and M5 human melanoma cells, respectively.).(In Vivo):In SCID female mice, DMU-212 (50 mg/kg; i.g.) inhibited tumor growth and lowered tumor burden.
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Synonyms——
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PathwayApoptosis
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TargetApoptosis
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RecptorTubulin polymerization
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Research Area——
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Indication——
Chemical Information
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CAS Number134029-62-2
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Formula Weight300.4
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Molecular FormulaC18H20O4
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Purity>98% (HPLC)
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Solubility——
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SMILESCOC1=CC=C(/C=C/C2=CC(OC)=C(OC)C(OC)=C2)C=C1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Schneider Y, et al. Resveratrol analog (Z)-3,5,4'-trimethoxystilbene is a potent anti-mitotic drug inhibiting tubulin polymerization. Int J Cancer. 2003 Nov 1;107(2):189-96.
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