DMPO

Research use only, not for human use.

DMPO is a kind of water-soluble nitric oxide spin trap, which allows the measurement of oxygen-centered free radicals in biological systems at room temperature using electron spin resonance.

DMPO is a kind of water-soluble nitric oxide spin trap, which allows the measurement of oxygen-centered free radicals in biological systems at room temperature using electron spin resonance. It has a high reaction rate constant for superoxide and hydroxyl radicals and distinguishes simultaneously among a variety of important biologically generated free radicals.(In Vitro):It was demonstrated in red blood cells and in hamster V79 cells that the DMPO spin adducts of ·O2? and ·OH are metabolized very rapidly so that even if formed, they may not be detected in many experiments with cells . (In Vivo):When DMPO perfused the heart at 100 μm/L, it attenuated the development of reperfusion arrhythmias during the first 10 min of reperfusion and improved the functional recovery of the heart during reperfusion. Without treatment, 55% of hearts showed irreversible ventricular fibrillation, and this was completely prevented by DMPO, due to its function of traping·O2? and ·OH radicals .

Western Blot Analysis Cell Line:BAEC cells Concentration:100 μM Incubation Time:12 and 24?h Result:Increased p-eNOS and p-Akt level.

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5,5-Dimethyl-1-pyrroline N-oxide

Others

Other Targets

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3317-61-1

113.16

C6H11NO

>98% (HPLC)

In Vitro:?H2O : ≥ 100 mg/mL (883.70 mM))

CC1(C)CCC=[N+]1[O-]

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(-20℃)

With Ice Pack

≥ 2 years