DMPO
CAS No. 3317-61-1
DMPO ( 5,5-Dimethyl-1-pyrroline N-oxide )
Catalog No. M27624 CAS No. 3317-61-1
DMPO is a kind of water-soluble nitric oxide spin trap, which allows the measurement of oxygen-centered free radicals in biological systems at room temperature using electron spin resonance.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
25MG | 35 | In Stock |
|
50MG | 58 | In Stock |
|
100MG | 88 | In Stock |
|
200MG | 140 | In Stock |
|
500MG | 236 | In Stock |
|
1G | Get Quote | In Stock |
|
Biological Information
-
Product NameDMPO
-
NoteResearch use only, not for human use.
-
Brief DescriptionDMPO is a kind of water-soluble nitric oxide spin trap, which allows the measurement of oxygen-centered free radicals in biological systems at room temperature using electron spin resonance.
-
DescriptionDMPO is a kind of water-soluble nitric oxide spin trap, which allows the measurement of oxygen-centered free radicals in biological systems at room temperature using electron spin resonance. It has a high reaction rate constant for superoxide and hydroxyl radicals and distinguishes simultaneously among a variety of important biologically generated free radicals.(In Vitro):It was demonstrated in red blood cells and in hamster V79 cells that the DMPO spin adducts of ·O2? and ·OH are metabolized very rapidly so that even if formed, they may not be detected in many experiments with cells . (In Vivo):When DMPO perfused the heart at 100 μm/L, it attenuated the development of reperfusion arrhythmias during the first 10 min of reperfusion and improved the functional recovery of the heart during reperfusion. Without treatment, 55% of hearts showed irreversible ventricular fibrillation, and this was completely prevented by DMPO, due to its function of traping·O2? and ·OH radicals .
-
Synonyms5,5-Dimethyl-1-pyrroline N-oxide
-
PathwayOthers
-
TargetOther Targets
-
Recptor——
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number3317-61-1
-
Formula Weight113.2
-
Molecular FormulaC6H11NO
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESCC1(C)CCC=[N+]1[O-]
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Guo L, et al. Comparative analysis of steroidal saponins in four Dioscoreae herbs by high performanceliquid chromatography coupled with mass spectrometry. J Pharm Biomed Anal. 2016 Jan 5;117:91-8.
molnova catalog
related products
-
15-Deoxypulic acid
15-Deoxypulic acid is a natural product of Pulicaria, Asteraceae. 15-Deoxypulic acid can be used as a reference standard.
-
2'3'5'-triacetyl-5-A...
2'3'5'-triacetyl-5-Azacytidine is a prodrug form of 5-azacytidine that may be rapidly absorbed orally.
-
HCV-IN-30
HCV-IN-30 is an HCV NS5A replication complex inhibitor (IC50s: 901 and 102 nM for genotypes 1a and 1b replicons).