DMPO

CAS No. 3317-61-1

DMPO ( 5,5-Dimethyl-1-pyrroline N-oxide )

Catalog No. M27624 CAS No. 3317-61-1

DMPO is a kind of water-soluble nitric oxide spin trap, which allows the measurement of oxygen-centered free radicals in biological systems at room temperature using electron spin resonance.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
25MG 35 In Stock
50MG 58 In Stock
100MG 88 In Stock
200MG 140 In Stock
500MG 236 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    DMPO
  • Note
    Research use only, not for human use.
  • Brief Description
    DMPO is a kind of water-soluble nitric oxide spin trap, which allows the measurement of oxygen-centered free radicals in biological systems at room temperature using electron spin resonance.
  • Description
    DMPO is a kind of water-soluble nitric oxide spin trap, which allows the measurement of oxygen-centered free radicals in biological systems at room temperature using electron spin resonance. It has a high reaction rate constant for superoxide and hydroxyl radicals and distinguishes simultaneously among a variety of important biologically generated free radicals.(In Vitro):It was demonstrated in red blood cells and in hamster V79 cells that the DMPO spin adducts of ·O2? and ·OH are metabolized very rapidly so that even if formed, they may not be detected in many experiments with cells . (In Vivo):When DMPO perfused the heart at 100 μm/L, it attenuated the development of reperfusion arrhythmias during the first 10 min of reperfusion and improved the functional recovery of the heart during reperfusion. Without treatment, 55% of hearts showed irreversible ventricular fibrillation, and this was completely prevented by DMPO, due to its function of traping·O2? and ·OH radicals .
  • Synonyms
    5,5-Dimethyl-1-pyrroline N-oxide
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    3317-61-1
  • Formula Weight
    113.2
  • Molecular Formula
    C6H11NO
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CC1(C)CCC=[N+]1[O-]
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Guo L, et al. Comparative analysis of steroidal saponins in four Dioscoreae herbs by high performanceliquid chromatography coupled with mass spectrometry. J Pharm Biomed Anal. 2016 Jan 5;117:91-8.
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