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DMA

CAS No. 188860-26-6

DMA( —— )

Catalog No. M23862 CAS No. 188860-26-6

DMA is a fluorescent agent (λex=340 nm, λem=478 nm).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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100MG 525 In Stock
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Biological Information

  • Product Name
    DMA
  • Note
    Research use only, not for human use.
  • Brief Description
    DMA is a fluorescent agent (λex=340 nm, λem=478 nm).
  • Description
    DMA is a fluorescent agent (λex=340 nm, λem=478 nm).
  • In Vitro
    The newly synthesized bisbenzimidazole derivatives DMA (6c)is evaluated for their cytotoxicity against human tumor cell lines, which are cervix carcinoma cell line (HeLa), breast carcinoma cell line (MCF7) and brain glioma cell line (U87) in comparison to Hoechst. In case of MCF7, the IC50 is observed at 5.3 μM for DMA. The IC50 determined in the case of HeLa is 3.4 μM for DMA.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    188860-26-6
  • Formula Weight
    468.55
  • Molecular Formula
    C27H28N6O2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 54 mg/mL (115.25 mM)
  • SMILES
    CN1CCN(C2=CC=C3C(N=C(C4=CC=C5C(N=C(C6=CC=C(OC)C(OC)=C6)N5)=C4)N3)=C2)CC1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Singh M, et al. Synthesis and biological activity of novel inhibitors of topoisomerase I: 2-aryl-substituted 2-bis-1H-benzimidazoles. Eur J Med Chem. 2011 Feb;46(2):659-69.
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