DM4 ( Ravtansine )

Catalog No. M24795 CAS No. 796073-69-3

DM4 can be used in the preparation of antibody drug conjugate and it is an antitubulin agent. It can inhibit cell division.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
2MG	40	In Stock
5MG	65	In Stock
10MG	120	In Stock
25MG	230	In Stock
50MG	403	In Stock
100MG	Get Quote	In Stock
200MG	Get Quote	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

DM4
Note

Research use only, not for human use.
Brief Description

DM4 can be used in the preparation of antibody drug conjugate and it is an antitubulin agent. It can inhibit cell division.
Description

DM4 can be used in the preparation of antibody drug conjugate and it is an antitubulin agent. It can inhibit cell division.
Synonyms

Ravtansine
Pathway

Others
Target

Other Targets
Recptor

Others
Research Area

——
Indication

——

Chemical Information

CAS Number

796073-69-3
Formula Weight

780.4
Molecular Formula

C38H54ClN3O10S
Purity

>98% (HPLC)
Solubility

DMSO: 99 mg/mL (126.86 mM; Need ultrasonic)
SMILES

CO[C@@H]1/C=C/C=C(Cc2cc(N(C(C[C@@H]([C@@]3(O[C@H]3[C@@H]([C@@H]4C[C@]1(NC(O4)=O)O)C)C)OC([C@@H](N(C(CCC(C)(S)C)=O)C)C)=O)=O)C)c(Cl)c(OC)c2)\C
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Tang R, et al. P-gp activity is a critical resistance factor against AVE9633 and DM4 cytotoxicity in leukaemia cell lines, but not a major mechanism of chemoresistance in cells from acute myeloid leukaemia patients. BMC Cancer. 2009 Jun 23;9:199.

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