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DM4
CAS No. 796073-69-3
DM4 ( Ravtansine )
Catalog No. M24795 CAS No. 796073-69-3
DM4 can be used in the preparation of antibody drug conjugate and it is an antitubulin agent. It can inhibit cell division.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 40 | In Stock |
|
| 5MG | 65 | In Stock |
|
| 10MG | 120 | In Stock |
|
| 25MG | 230 | In Stock |
|
| 50MG | 403 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameDM4
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NoteResearch use only, not for human use.
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Brief DescriptionDM4 can be used in the preparation of antibody drug conjugate and it is an antitubulin agent. It can inhibit cell division.
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DescriptionDM4 can be used in the preparation of antibody drug conjugate and it is an antitubulin agent. It can inhibit cell division.
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SynonymsRavtansine
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number796073-69-3
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Formula Weight780.4
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Molecular FormulaC38H54ClN3O10S
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Purity>98% (HPLC)
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SolubilityDMSO: 99 mg/mL (126.86 mM; Need ultrasonic)
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SMILESCO[C@@H]1/C=C/C=C(Cc2cc(N(C(C[C@@H]([C@@]3(O[C@H]3[C@@H]([C@@H]4C[C@]1(NC(O4)=O)O)C)C)OC([C@@H](N(C(CCC(C)(S)C)=O)C)C)=O)=O)C)c(Cl)c(OC)c2)\C
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Tang R, et al. P-gp activity is a critical resistance factor against AVE9633 and DM4 cytotoxicity in leukaemia cell lines, but not a major mechanism of chemoresistance in cells from acute myeloid leukaemia patients. BMC Cancer. 2009 Jun 23;9:199.
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