Cart
sales@molnova.com
DHX9-IN-2
CAS No. 2973395-71-8
DHX9-IN-2( —— )
Catalog No. M37315 CAS No. 2973395-71-8
DHX9-IN-2 is an inhibitor targeting ATP-dependent RNA de-helicase A (DHX9) with anticancer and antitumor activity for cancer research.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 149 | Get Quote |
|
| 5MG | 242 | Get Quote |
|
| 10MG | 376 | Get Quote |
|
| 25MG | 753 | Get Quote |
|
| 50MG | 1178 | Get Quote |
|
| 100MG | 1872 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameDHX9-IN-2
-
NoteResearch use only, not for human use.
-
Brief DescriptionDHX9-IN-2 is an inhibitor targeting ATP-dependent RNA de-helicase A (DHX9) with anticancer and antitumor activity for cancer research.
-
DescriptionDHX9-IN-2 (example 31)is an inhibitor of ATP-dependent RNA helicase A (DHX9), with the IC50 of 0.0698 nM that has antitumor activity.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayCell Cycle/DNA Damage
-
TargetDNA/RNA Synthesis
-
RecptorDNA/RNA Synthesis
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2973395-71-8
-
Formula Weight421.92
-
Molecular FormulaC18H16ClN3O3S2
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 100 mg/mL (237.01 mM; Ultrasonic )
-
SMILESO=C(NC1=CC(Cl)=CC(=C1)NS(=O)(=O)C)C=2SC=C(C2)C=3N=CC=CC3C
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. DANIELS Matthew H., et al. Preparation of imidazopyridines, thienopyrimidines, pyrrolopyrimidines and related heterocycles as inhibitors of RNA helicase DHX9 useful in treatment of cancers. World Intellectual Property Organization, WO2023154519 A1 2023-08-17
molnova catalog
related products
-
JH-RE-06
JH-RE-06 disrupts mutagenic translesion synthesis (TLS) by preventing the recruitment of mutagenic POLζ. JH-RE-06 is an effective REV1-REV7 interface inhibitor (IC50=0.78 μM; Kd=0.42 μM), which targets REV1 that interacts with the REV7 subunit of POLζ. JH-RE-06 also improves chemotherapy.
-
Treosulfan
Treosulfan is a bifunctional alkylating agent. It also has activity in ovarian cancer and other solid tumor types.
-
3-O-Acetyl-beta-bosw...
3-O-Acetyl-beta-boswellic acid has antitumor activity, it inhibits synthesis of DNA, RNA and protein in human leukemia HL-60 cells in a dose dependent manner with IC50 values ranging from 0.6 to 7.1 microM.
