DHODH-IN-17( —— )

Catalog No. M35407 CAS No. 16344-26-6

DHODH-IN-17 is a human DHODH inhibitor with an IC50 of 0.40 μM. DHODH-IN-17 is a 2- anilino nicotinic acid that can be used in the study of acute myeloid leukemia (AML).

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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10MG	100	In Stock
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50MG	293	In Stock
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500MG	888	In Stock
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Biological Information

Product Name

DHODH-IN-17
Note

Research use only, not for human use.
Brief Description

DHODH-IN-17 is a human DHODH inhibitor with an IC50 of 0.40 μM. DHODH-IN-17 is a 2- anilino nicotinic acid that can be used in the study of acute myeloid leukemia (AML).
Description

DHODH-IN-17, a 2-anilino nicotinic acid, is a human DHODH inhibitor (IC50=0.40 μM). DHODH-IN-17 can be used for theresearch of acute myeloid leukemia (AML).
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Metabolic Enzyme/Protease
Target

Dehydrogenase
Recptor

Dehydrogenase
Research Area

——
Indication

——

Chemical Information

CAS Number

16344-26-6
Formula Weight

248.67
Molecular Formula

C12H9ClN2O2
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 83.33 mg/mL (335.10 mM; Ultrasonic )
SMILES

OC(=O)C1=C(NC2=CC=C(Cl)C=C2)N=CC=C1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Lewis TA, et al. Development of ML390: A Human DHODH Inhibitor That Induces Differentiation in Acute Myeloid Leukemia. ACS Med Chem Lett. 2016;7(12):1112-1117.

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