DENV-IN-5

CAS No. 2375781-06-7

DENV-IN-5( —— )

Catalog No. M35702 CAS No. 2375781-06-7

Denv-in-5 is an effective and selective dengue virus (DENV) inhibitor with EC50 values of 1.47, 9.23, 7.08, 8.91 μM for denV-I-IV and 0.1512 μM for HIV-1IIIB.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 714 Get Quote
5MG 1017 Get Quote
10MG 1359 Get Quote
25MG 1932 Get Quote
50MG 2374 Get Quote
100MG 3060 Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    DENV-IN-5
  • Note
    Research use only, not for human use.
  • Brief Description
    Denv-in-5 is an effective and selective dengue virus (DENV) inhibitor with EC50 values of 1.47, 9.23, 7.08, 8.91 μM for denV-I-IV and 0.1512 μM for HIV-1IIIB.
  • Description
    DENV-IN-5 (Compound 4b) is a dengue virus (DENV) inhibitor with EC50s of 1.47, 9.23, 7.08 and 8.91 μM against DENV-I ~ IV replication, respectively. DENV-IN-5 also inhibits HIV-1IIIB strain with an EC50 of 0.1512 μM.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Virus Protease | HIV Protease
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2375781-06-7
  • Formula Weight
    478.99
  • Molecular Formula
    C23H25ClF2N4OS
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ClC1=C(NN=C1CSC=2NC(CC3CCCCC3)=C(CC)C(=O)N2)C4=CC(F)=C(F)C=C4
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Rui RM, et al. C6-structural optimizations of 2-aryl-1H-pyrazole-S-DABOs: From anti-HIV to anti-DENV activity. Bioorg Chem. 2022 Feb;119:105494.?
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