DC661
CAS No. 1872387-43-3
DC661 ( DC-661;DC 661 )
Catalog No. M12900 CAS No. 1872387-43-3
DC661 (DC-661) is a novel dimeric chloroquine (CQ) that is capable of deacidifying the lysosome and inhibiting autophagy significantly better than HCQ, targets palmitoyl-protein thioesterase 1 (PPT1).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
2MG | 96 | In Stock |
|
5MG | 178 | In Stock |
|
10MG | 302 | In Stock |
|
25MG | 516 | In Stock |
|
50MG | 740 | In Stock |
|
100MG | 1017 | In Stock |
|
200MG | Get Quote | In Stock |
|
500MG | Get Quote | In Stock |
|
1G | Get Quote | In Stock |
|
Biological Information
-
Product NameDC661
-
NoteResearch use only, not for human use.
-
Brief DescriptionDC661 (DC-661) is a novel dimeric chloroquine (CQ) that is capable of deacidifying the lysosome and inhibiting autophagy significantly better than HCQ, targets palmitoyl-protein thioesterase 1 (PPT1).
-
DescriptionDC661 (DC-661) is a novel dimeric chloroquine (CQ) that is capable of deacidifying the lysosome and inhibiting autophagy significantly better than HCQ, targets palmitoyl-protein thioesterase 1 (PPT1); inhibits autophagy and causes significant impairment of tumor growth.
-
SynonymsDC-661;DC 661
-
PathwayAutophagy
-
TargetAutophagy
-
RecptorAutophagy
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1872387-43-3
-
Formula Weight550.61
-
Molecular FormulaC33H41Cl2N3
-
Purity>98% (HPLC)
-
SolubilityDMSO : 62.5 mg/mL 113.11 mM;H2O : < 0.1 mg/mL
-
SMILESCN(CCCCCCNC1=CC=NC2=CC(Cl)=CC=C12)CCCCCCNC3=CC=NC4=CC(Cl)=CC=C34
-
Chemical NameN1-(6-chloronaphthalen-1-yl)-N6-(6-((6-chloronaphthalen-1-yl)amino)hexyl)-N6-methylhexane-1,6-diamine
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Rebecca VW, et al. Cancer Discov. 2018 Nov 15. pii: CD-18-0706. doi: 10.1158/2159-8290.CD-18-0706.
molnova catalog
related products
-
DC661
DC661 (DC-661) is a novel dimeric chloroquine (CQ) that is capable of deacidifying the lysosome and inhibiting autophagy significantly better than HCQ, targets palmitoyl-protein thioesterase 1 (PPT1).
-
AUTEN-67
A small molecule autophagy enhancer that specificly inhibits myotubularin-related phosphatase MTMR14; at concentrations of 2, 10, and 100 uM, AUTEN-67 inhibits MTMR14 by nearly 3%, 25%, and 70%, respectively.
-
AUTEN-99 hydrobromid...
A small molecule autophagy enhancer that inhibit the myotubularin-related phosphatase MTMR14/Jumpy.