Cart
sales@molnova.com
DBCO-Amine
CAS No. 1255942-06-3
DBCO-Amine( DBCO amine )
Catalog No. M11043 CAS No. 1255942-06-3
A simple DBCO-containing building block used to derivatize carboxyl groups in the presence of activators (e.g. EDC, or DCC) or activated esters (e.g. NHS esters) with DBCO moiety through a stable amide bond.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 43 | In Stock |
|
| 10MG | 71 | In Stock |
|
| 25MG | 115 | In Stock |
|
| 50MG | 168 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameDBCO-Amine
-
NoteResearch use only, not for human use.
-
Brief DescriptionA simple DBCO-containing building block used to derivatize carboxyl groups in the presence of activators (e.g. EDC, or DCC) or activated esters (e.g. NHS esters) with DBCO moiety through a stable amide bond.
-
DescriptionA simple DBCO-containing building block used to derivatize carboxyl groups in the presence of activators (e.g. EDC, or DCC) or activated esters (e.g. NHS esters) with DBCO moiety through a stable amide bond; A click chemistry tool used to conjugate DBCO-PEG4-MMAF to the introduced non-natural amino acid pAMF using a noncleavable linker.
-
In Vitro——
-
In Vivo——
-
SynonymsDBCO amine
-
PathwayAntibody Drug Conjugates (ADC)
-
TargetADCs Linker/Click Chemistry
-
RecptorADCs Linker/Click Chemistry
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1255942-06-3
-
Formula Weight276.339
-
Molecular FormulaC18H16N2O
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESO=C(CCN)N1CC2=C(C=CC=C2)C#CC3=C1C=CC=C3
-
Chemical Name3-Amino-1-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-1-propanone
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Currier NV, et al. Mol Cancer Ther. 2016 Jun;15(6):1291-300.
molnova catalog
related products
-
Boc-Val-Cit-PAB
Boc-Val-Cit-PAB is a cleavable ADC linker. Boc-Val-Cit-PAB used in the synthesis of antibody-drug conjugates (ADCs).?
-
DBCO-PEG4 amine
DBCO-PEG4 amine (ADIBO-PEG4-amine) is a Click Chemistry intermidate used for antibody-drug conjugates.
-
DBCO-NHS ester 2
DBCO-NHS ester 2 is a derivative of DBCO (Dibenzylcyclooctyne) used in Cu-free click chemistry.
