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DBCO-Amine
CAS No. 1255942-06-3
DBCO-Amine( DBCO amine )
Catalog No. M11043 CAS No. 1255942-06-3
A simple DBCO-containing building block used to derivatize carboxyl groups in the presence of activators (e.g. EDC, or DCC) or activated esters (e.g. NHS esters) with DBCO moiety through a stable amide bond.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 43 | In Stock |
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| 10MG | 71 | In Stock |
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| 25MG | 115 | In Stock |
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| 50MG | 168 | In Stock |
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| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
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Biological Information
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Product NameDBCO-Amine
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NoteResearch use only, not for human use.
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Brief DescriptionA simple DBCO-containing building block used to derivatize carboxyl groups in the presence of activators (e.g. EDC, or DCC) or activated esters (e.g. NHS esters) with DBCO moiety through a stable amide bond.
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DescriptionA simple DBCO-containing building block used to derivatize carboxyl groups in the presence of activators (e.g. EDC, or DCC) or activated esters (e.g. NHS esters) with DBCO moiety through a stable amide bond; A click chemistry tool used to conjugate DBCO-PEG4-MMAF to the introduced non-natural amino acid pAMF using a noncleavable linker.
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In Vitro——
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In Vivo——
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SynonymsDBCO amine
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PathwayAntibody Drug Conjugates (ADC)
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TargetADCs Linker/Click Chemistry
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RecptorADCs Linker/Click Chemistry
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Research Area——
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Indication——
Chemical Information
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CAS Number1255942-06-3
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Formula Weight276.339
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Molecular FormulaC18H16N2O
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C(CCN)N1CC2=C(C=CC=C2)C#CC3=C1C=CC=C3
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Chemical Name3-Amino-1-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-1-propanone
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Currier NV, et al. Mol Cancer Ther. 2016 Jun;15(6):1291-300.
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