D75-4590

CAS No. 384376-42-5

D75-4590( —— )

Catalog No. M35527 CAS No. 384376-42-5

D75-4590 is a β-1,6-Glucan inhibitor. As glucan is a major component of the cell wall, specifically β-1,6-Glucan, D75-4590 can fight fungal infections by inhibiting its synthetase.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 46 Get Quote
5MG 55 Get Quote
10MG 93 Get Quote
25MG 200 Get Quote
50MG 318 Get Quote
100MG 449 Get Quote
500MG 888 Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    D75-4590
  • Note
    Research use only, not for human use.
  • Brief Description
    D75-4590 is a β-1,6-Glucan inhibitor. As glucan is a major component of the cell wall, specifically β-1,6-Glucan, D75-4590 can fight fungal infections by inhibiting its synthetase.
  • Description
    D75-4590, a pyridobenzimidazole derivative and a β-1,6-glucan synthesis inhibitor, possesses antifungal activity.
  • In Vitro
    D75-4590 has activities against a variety of Candida species, including fluconazole-resistant strains. Most strains of C. albicans, C. tropicalis, and C. parapsilosis displayed trailing growth phenomena similar to those observed in the presence of azoles.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    384376-42-5
  • Formula Weight
    349.47
  • Molecular Formula
    C21H27N5
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 50 mg/mL (143.07 mM; Ultrasonic (<60°C)
  • SMILES
    CCN(CC)CCNc1c(CC)c(C)c(C#N)c2nc3ccccc3n12
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Akihiro Kitamura, et al. Discovery of a small-molecule inhibitor of {beta}-1,6-glucan synthesis. Antimicrob Agents Chemother. 2009 Feb;53(2):670-7.?
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