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D-Leucine
CAS No. 328-38-1
D-Leucine( (R)-Leucine )
Catalog No. M24264 CAS No. 328-38-1
D-Leucine potently terminates seizures even after the onset of seizure activity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 500MG | 37 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameD-Leucine
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NoteResearch use only, not for human use.
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Brief DescriptionD-Leucine potently terminates seizures even after the onset of seizure activity.
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DescriptionD-Leucine potently terminates seizures even after the onset of seizure activity. D-leucine reduces long-term potentiation but had no effect on basal synaptic transmission in vitro.
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In VitroIn a screen of candidate neuronal receptors, D-leucine failed to compete for binding by cognate ligands, potentially suggesting a novel target. Even at low doses, D-leucine suppressed ongoing seizures at least as effectively as diazepam. These studies raise the possibility that D-leucine may represent a new class of anti-seizure agents, and that D-leucine may have a previously unknown function in eukaryotes.
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In Vivo——
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Synonyms(R)-Leucine
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PathwayProteasome/Ubiquitin
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TargetEndogenous Metabolite
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RecptorHuman Endogenous Metabolite
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Research Area——
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Indication——
Chemical Information
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CAS Number328-38-1
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Formula Weight131.17
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Molecular FormulaC6H13NO2
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Purity>98% (HPLC)
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SolubilityDMSO : < 1 mg/mL (ultrasonic;warming;heat to 60°C) (insoluble or slightly soluble)
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SMILESCC(C)C[C@H](C(O)=O)N
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Xiaoyu Cao, et al. Combination of PARP Inhibitor and Temozolomide to Suppress Chordoma Progression. J Mol Med (Berl). 2019 Aug;97(8):1183-1193
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