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Cyclopenthiazide

CAS No. 742-20-1

Cyclopenthiazide( Cyclomethiazide | Su-8341 | SU 8341 )

Catalog No. M24749 CAS No. 742-20-1

Cyclopenthiazide is a thiazide diuretic used to treat hypertension and heart failure. It decreases the excretion of calcium ions and uric acid and increases the excretion of sodium and potassium ions.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Cyclopenthiazide
  • Note
    Research use only, not for human use.
  • Brief Description
    Cyclopenthiazide is a thiazide diuretic used to treat hypertension and heart failure. It decreases the excretion of calcium ions and uric acid and increases the excretion of sodium and potassium ions.
  • Description
    Cyclopenthiazide is a thiazide diuretic used to treat hypertension and heart failure. It decreases the excretion of calcium ions and uric acid and increases the excretion of sodium and potassium ions.(In Vivo):Cyclopenthiazide (0.5 mg/kg; i.p.; daily, for 3 days; female Wistar rats) increases the excretion of p-aminohippurate (PAH) .
  • In Vitro
    ——
  • In Vivo
    Cyclopenthiazide (0.5 mg/kg; i.p.; daily, for 3 days; female Wistar rats) increases the excretion of p-aminohippurate (PAH) . Animal Model:Female Wistar rats Dosage:0.5 mg/kg Administration:Intraperitoneal injection; daily, for 3 daysResult:Stimulated p-aminohippurate (PAH) excretion.
  • Synonyms
    Cyclomethiazide | Su-8341 | SU 8341
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    742-20-1
  • Formula Weight
    379.88
  • Molecular Formula
    C13H18ClN3O4S2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:Soluble; Water:Insoluble
  • SMILES
    NS(c(cc(c(NC(CC1CCCC1)N1)c2)S1(=O)=O)c2Cl)(=O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Krum H, Jackson B, Conway EL, Howes LG, Johnston CI, Louis WJ. Steady-state pharmacokinetics and pharmacodynamics of cilazapril in the presence and absence of cyclopenthiazide. J Cardiovasc Pharmacol. 1992 Sep;20(3):451-7. PubMed PMID: 1279292.
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