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Cyasterone

CAS No. 17086-76-9

Cyasterone ( Cyasterone; AI3-44890; AI3 44890 )

Catalog No. M18117 CAS No. 17086-76-9

Cyasterone, a natural EGFR inhibitor, can inhibit the growth of A549 and MGC823 cells, via regulating EGFR signaling pathway, it may be a promising anti-cancer agent.

Purity : 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 58 In Stock
10MG 102 In Stock
25MG 192 In Stock
50MG 287 In Stock
100MG 428 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    Cyasterone
  • Note
    Research use only, not for human use.
  • Brief Description
    Cyasterone, a natural EGFR inhibitor, can inhibit the growth of A549 and MGC823 cells, via regulating EGFR signaling pathway, it may be a promising anti-cancer agent.
  • Description
    Cyasterone was demonstrated potential inhibition effect in skin carcinoma cells.
  • Synonyms
    Cyasterone; AI3-44890; AI3 44890
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    EGFR
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    17086-76-9
  • Formula Weight
    520.66
  • Molecular Formula
    C29H44O8
  • Purity
    98%
  • Solubility
    ——
  • SMILES
    O1C(=O)[C@H]([C@@H]([C@H]1C)C[C@H]([C@@](C)([C@H]1CC[C@]2(C3=CC(=O)[C@@H]4C[C@H]([C@H](C[C@@]4([C@H]3CC[C@]12C)C)O)O)O)O)O)C
  • Chemical Name
    5-beta-Stigmast-7-en-26-oic acid, 2-beta,3-beta,14,20,22,28-hexahydroxy-6-oxo-, gamma-lactone, (22R,24S,25S,28R)-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Hirayama Y,et al. Stereochemical assignment of C-24 and C-25 of amarasterone A, a putative biosynthetic intermediate of cyasterone. J Org Chem. 2014 Jun 20;79(12):5471-7.
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