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Conessine

CAS No. 546-06-5

Conessine ( Conessinum; Konessin; Neriine; Roquessine; Wrightine )

Catalog No. M24532 CAS No. 546-06-5

Conessine, a steroidal alkaloid isolated from Holarrhena floribunda, interacts with the histamine H3 receptor and has anti-malarial activity.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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5MG 64 In Stock
10MG 91 In Stock
25MG 165 In Stock
50MG 237 In Stock
100MG 405 In Stock
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Biological Information

  • Product Name
    Conessine
  • Note
    Research use only, not for human use.
  • Brief Description
    Conessine, a steroidal alkaloid isolated from Holarrhena floribunda, interacts with the histamine H3 receptor and has anti-malarial activity.
  • Description
    Conessine, a steroidal alkaloid isolated from Holarrhena floribunda, interacts with the histamine H3 receptor and has anti-malarial activity.
  • Synonyms
    Conessinum; Konessin; Neriine; Roquessine; Wrightine
  • Pathway
    GPCR/G Protein
  • Target
    Histamine Receptor
  • Recptor
    H3 receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    546-06-5
  • Formula Weight
    356.6
  • Molecular Formula
    C24H40N2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:Soluble
  • SMILES
    CN(C)[C@@H](C1)CC[C@]([C@@H]2CC3)(C)C1=CC[C@H]2[C@H]4CC[C@@H]5[C@]43CN(C)[C@@H]5C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Kim H, Lee KI, Jang M, Namkoong S, Park R, Ju H, Choi I, Oh WK, Park J. Conessine Interferes with Oxidative Stress-Induced C2C12 Myoblast Cell Death through Inhibition of Autophagic Flux. PLoS One. 2016 Jun 3;11(6):e0157096. doi: 10.1371/journal.pone.0157096. eCollection 2016. PubMed PMID: 27257813; PubMed Central PMCID: PMC4892631.
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