Cart
sales@molnova.com
Complement C5-IN-1
CAS No. 2365402-67-9
Complement C5-IN-1( —— )
Catalog No. M32854 CAS No. 2365402-67-9
Complement C5-IN-1 is a small-molecule inhibitor of complement component 5 protein (C5).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 236 | Get Quote |
|
| 5MG | 303 | Get Quote |
|
| 10MG | 438 | Get Quote |
|
| 25MG | 657 | Get Quote |
|
| 50MG | 872 | Get Quote |
|
| 100MG | 1161 | Get Quote |
|
| 500MG | 2331 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameComplement C5-IN-1
-
NoteResearch use only, not for human use.
-
Brief DescriptionComplement C5-IN-1 is a small-molecule inhibitor of complement component 5 protein (C5).
-
DescriptionComplement C5-IN-1 (Compound 7) is a small-molecule inhibitor of complement component 5 protein (C5). Complement C5-IN-1 interacts with C5 to prevent its cleavage by the C5 convertase and blocks zymosan-induced the membrane-attack complex (MAC) deposition in 50% human whole blood with an IC50 of 0.77 μM.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayImmunology/Inflammation
-
TargetComplement System
-
RecptorComplement System
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2365402-67-9
-
Formula Weight444.52
-
Molecular FormulaC24H32N2O6
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : ≥ 100 mg/mL (224.96 mM)
-
SMILESCOc1ccccc1[C@H](C)NC(=O)Nc1cc(OCCCC(C)C)c(OC)cc1C(O)=O
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Jendza K, et al. A small-molecule inhibitor of C5 complement protein. Nat Chem Biol. 2019 Jul;15(7):666-668.?
molnova catalog
related products
-
Complement C5-IN-1
Complement C5-IN-1 is a small-molecule inhibitor of complement component 5 protein (C5).
-
Ravulizumab
Ravulizumab (ALXN1210) is a humanized monoclonal antibody that specifically binds to human complement protein C5 with high affinity, targeting complement factor 5 to block complement activation.
-
EG01377 2HCl
EG01377 2HCl is a potent, bioavailable and selective inhibitor of neuropilin-1 (NRP1) with a Kd value of 1.32 μM and an IC50 value of 609 nM for both EG01377 2HCl against NRP1-a1 and NRP1-b1.
